DARS

Gene Symbol DARS
Entrez Gene 1615
Alt Symbol HBSL, aspRS
Species Human
Gene Type protein-coding
Description aspartyl-tRNA synthetase
Other Description aspartate tRNA ligase 1, cytoplasmic|aspartate--tRNA ligase, cytoplasmic|aspartyl-tRNA synthetase, cytoplasmic|cell proliferation-inducing gene 40 protein
Swissprots Q32Q69 D3DP77 Q2TNI3 P14868 A8K3J2 Q53YC5 Q68CR9 Q53HV4 Q9BW52
Accessions AAY15029 AAY24055 EAX11617 EAX11618 EAX11619 EAX11620 P14868 AK129521 AK222476 BAD96196 AK290607 BAF83296 AY762100 AAX07827 BC000629 AAH00629 BC107749 AAI07750 BI753718 BT006710 AAP35356 BU615302 BX101357 CR749809 CAH18669 DA597505 DQ890741 ABM81667 DQ893912 ABM84838 J05032 AAA35567 NM_001293312 NP_001280241 NM_001349 NP_001340
Function Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.
Subcellular Location Cytoplasm.
Tissue Specificity Expression in the developing and adult brain shows similar patterns. Highly expressed in the ventricular and subventricular zones, including hippocampal subfields, the midlateral temporaal cortex and the frontal polar cortex. The cerebellum, cereral cortex, hippocampus, and lateral ventricle show preferential neuronal expression. Expression in the peripheral neurons is evident in the colon. {ECO:0000269|PubMed:23643384}.
Top Pathways Aminoacyl-tRNA biosynthesis

DaRS CRISPR/Cas9 KO Plasmid (h) - sc-410473 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DaRS HDR Plasmid (h) - sc-410473-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DaRS Double Nickase Plasmid (h) - sc-410473-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DaRS Double Nickase Plasmid (h2) - sc-410473-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DaRS CRISPR Activation Plasmid (h) - sc-410473-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DaRS CRISPR Activation Plasmid (h2) - sc-410473-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DaRS Lentiviral Activation Particles (h) - sc-410473-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DaRS Lentiviral Activation Particles (h2) - sc-410473-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DaRS siRNA (h) - sc-94475 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DaRS shRNA Plasmid (h) - sc-94475-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DaRS shRNA (h) Lentiviral Particles - sc-94475-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DARS RNAi - H00001615-R01V from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human
Western Blot: DARS RNAi [H00001615-R01V] - Analysis of DARS over-expressed 293 cell line, cotransfected with DARS Validated Chimera RNAi or non-transfected control. Blot probed with H00001615-M01. GAPDH (36.1 kDa) used as loading control.

DARS RNAi - H00001615-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU038391 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6933 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6933 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05361 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05361

DARS siRNA (Human) - CRH1137 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DARS - MBS8211962 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DARS (NM_001349.2) - SHH274601 from Creative biogene

Category siRNA
Species Reactivities Human

Human DARS siRNA - orb261639 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DARS shRNA Plasmid (Human) - CHH1137 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DARS miRNA 3'UTR clone - MiUTR1H-02670 from Creative biogene

Species Reactivities Human
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