Gene Symbol | Il23r |
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Entrez Gene | 209590 |
Alt Symbol | IL-23R |
Species | Mouse |
Gene Type | protein-coding |
Description | interleukin 23 receptor |
Other Description | IL-23 receptor|interleukin-23 receptor |
Swissprots | Q8K4B4 |
Accessions | EDK98806 Q8K4B4 AF461423 AAM44230 BC112425 AAI12426 NM_144548 NP_653131 |
Function | Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
Tissue Specificity | Expressed by Th1, Th2 and dendritic cells. {ECO:0000269|PubMed:12023369}. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Inflammatory bowel disease (IBD) |
Anti-IL23 Receptor antibody [RM0110-6D34] - ab86640 from Abcam
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IL-23 R Antibody (RM0110-6D34) - NBP1-22488 from Novus Biologicals
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IL-23 R Antibody (753317) [PE] - FAB16861P-025 from Novus Biologicals
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IL-23 R Antibody (753317) [Alexa Fluor (R) 700] - FAB16861N-025 from Novus Biologicals
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IL-23 R Antibody (753317) [Alexa Fluor (R) 488] - FAB16861G-025 from Novus Biologicals
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IL-23 R Antibody (753317) [PerCP] - FAB16861C-025 from Novus Biologicals
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IL-23 R Antibody (753317) [Allophycocyanin] - FAB16861A-025 from Novus Biologicals
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IL23 Receptor antibody [6D34] - GTX53200 from GeneTex
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Anti -Interleukin 23 Receptor (IL-23 R, IL23R) (APC) - 145495 from USBiological Life Science
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Interleukin-23 receptor / IL23R (Extracell. Dom.) antibody - DM3578P from Acris Antibodies
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IL-23 receptor, Monoclonal Antibody - MBS690333 from MyBioSource
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BD Pharmingen™ PE Rat anti-Mouse IL-23 Receptor - 562497 from BD Biosciences
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BD Horizon™ BB515 Rat Anti-Mouse IL-23 Receptor - 565011 from BD Biosciences
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BD Pharmingen™ PerCP-Cy™5.5 Rat anti-Mouse IL-23 Receptor - 564828 from BD Biosciences
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BD Pharmingen™ PE Mouse anti-Mouse IL-23 Receptor - 562468 from BD Biosciences
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Rabbit anti-Mouse IL23 Receptor polyclonal antibody - DPABH-27666 from Creative Diagnostics
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IL23R antibody - N-terminal region (OASA06290) - OASA06290 from Aviva Systems Biology
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Purified anti-mouse IL-23R Antibody - 150902 from Biolegend
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PE anti-mouse IL-23R Antibody - 150903 from Biolegend
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BD OptiBuild™ BV605 Rat Anti-Mouse IL-23 Receptor - 744370 from BD Biosciences
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BD OptiBuild™ BV421 Rat Anti-Mouse IL-23 Receptor - 744368 from BD Biosciences
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BD OptiBuild™ BV650 Rat Anti-Mouse IL-23 Receptor - 744371 from BD Biosciences
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BD Horizon™ BB515 Rat Anti-Mouse IL-23 Receptor - 566212 from BD Biosciences
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BD OptiBuild™ BV421 Mouse Anti-Mouse IL-23 Receptor - 744042 from BD Biosciences
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BD OptiBuild™ BV711 Rat Anti-Mouse IL-23 Receptor - 744372 from BD Biosciences
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