ETS1

Gene Symbol ETS1
Entrez Gene 2113
Alt Symbol ETS-1, EWSR2, p54
Species Human
Gene Type protein-coding
Description v-ets avian erythroblastosis virus E26 oncogene homolog 1
Other Description Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1|protein C-ets-1|v-ets avian erythroblastosis virus E2 oncogene homolog 1
Swissprots Q16080 P14921 A9UL17 F5GYX9 Q96AC5 Q14278 Q6N087
Accessions AAA52409 EAW67709 EAW67710 EAW67711 EAW67712 P14921 AK001630 AK291840 BAF84529 AK301405 BAG62940 AL832693 AY943926 AAY19514 BC017314 AAH17314 BG035366 BM468663 BP365215 BT019452 AAV38259 BT019453 AAV38260 BX640634 CAE45783 CA407336 CR542254 CAG47050 J04101 AAA52410 S53284 S67063 AAB28747 S87905 X14798 CAA32903 XM_011542649 XP_011540951 XM_011542650 XP_011540952 XM_011542651 XP_011540953 XM_011542652 XP_011540954 NM_001143820 NP_001137292 NM_001162422 NP_001155894 NM_005238 NP_005229
Function Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion. {ECO:0000269|PubMed:10698492, ECO:0000269|PubMed:11909962, ECO:0000269|PubMed:15247905, ECO:0000269|PubMed:15592518}.
Subcellular Location Cytoplasm. Nucleus. Note=Delocalizes from nucleus to cytoplasm when coexpressed with isoform Ets-1 p27.
Tissue Specificity Highly expressed within lymphoid cells. Isoforms c-ETS-1A and Ets-1 p27 are both detected in all fetal tissues tested, but vary with tissue type in adult tissues. None is detected in brain or kidney. {ECO:0000269|PubMed:19377509, ECO:0000269|PubMed:20378371}.
Top Pathways Renal cell carcinoma, HTLV-I infection, Dorso-ventral axis formation

ETS-1 (D8O8A) Rabbit mAb - 14069 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D8O8A
Western blot analysis of extracts from various cell lines using ETS-1 (D8O8A) Rabbit mAb.

ETS-1 Antibody - 6258 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using ETS-1 Antibody.

Ets-1 (C-4) - sc-55581 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ets-1 (C-4): sc-55581. Western blot analysis of Ets-1 expression in NIH/3T3 (A) and KNRK (B) nuclear extracts.

Ets-1 (H-150) - sc-22802 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Ets-1 (H-150): sc-22802. Western blot analysis of Ets-1 expression in non-transfected: sc-117752 (A) and mouse Ets-1 transfected: sc-120130 (B) 293T whole cell lysates.

Ets-1 (N-276) - sc-111 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Ets-1 (N-276): sc-111. Western blot analysis of Ets-1 expression in Jurkat (A,B) nuclear extract.

Ets-1 (C-20) - sc-350 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Ets-1 (C-20): sc-350. Western blot analysis of Ets-1 expression in KNRK nuclear extract.

Ets-1/Ets-2 (C-275) - sc-112 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Ets-1/Ets-2 (C-275): sc-112. Western blot analysis of Ets-1/Ets-2 expression in MM-142 (A), KNRK (B) and 3611-RF (C) nuclear extracts.

Ets-1/Ets-2 (D-7) - sc-374509 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Ets-1/Ets-2 (D-7): sc-374509. Western blot analysis of Ets-1/Ets-2 expression in KNRK nuclear extract.

Anti-ETS1 (phospho T38) antibody - ab59179 from Abcam

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ETS1 (phospho T38) antibody (ab59179) at 1/1000 dilutionLane 1 : Human A2058 whole cell lysateLane 2 : Human A375 whole cell lysateLysates/proteins at 50 µg per lane.SecondaryHRP-conjugated Hourse anti-rabbit IgG polyclonal at 1/2000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-ETS1 antibody - ab186844 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of rat lung tissue labelling ETS1 with ab186844 at 1/200. Magnification: 400x.

Anti-ETS1 antibody - ab59217 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab59217 at 1/50 - 1/100 dilution staining ETS1 in human lung carcinoma by Immunohistochemistry, Paraffin embedded tissue, in the absence or presence of the immunising peptide.

Anti-ETS1 antibody [1G11] - ab10936 from Abcam

Prices $384.00
Sizes 250 µl
Host Mouse
Clonality Monoclonal
Clone 1G11
All lanes : Anti-ETS1 antibody [1G11] (ab10936) at 5 µg/mlLane 1 : A431 (Human epithelial carcinoma cell line) Whole Cell Lysate (ab52255)Lane 2 : A549 (Human lung adenocarcinoma epithelial cell line) Whole Cell Lysate (ab70721)Lysates/proteins at 20 µg per lane.SecondaryGoat Anti-Mouse IgG H&L (HRP) preadsorbed (ab97040) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-ETS1 antibody [8A8] - ab96478 from Abcam

Prices $384.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 8A8
All lanes : Anti-ETS1 antibody [8A8] (ab96478) at 1/500 dilutionLane 1 : Jurkat cell lysateLane 2 : HepG2 cell lysateLane 3 : ETS1-hIgGFc transfected HEK293 cell lysate

Anti-ETS1 antibody [EPR546(2)] - ab109212 from Abcam

Prices $381.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR546(2)
Overlay histogram showing Jurkat cells stained with ab109212 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab109212, 1/1000 dilution) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-rabbit IgG (H&L) (ab150077) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (0.1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in Jurkat cells fixed with 4% paraformaldehyde (10 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-ETS1 / ETS-1 Antibody - LS-C310289 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ETS1 / ETS-1 Antibody (aa46-74) - LS-C329520 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ETS1 / ETS-1 Antibody (aa95-144) - LS-C201211 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Thyroid tumor. ETS1 antibody dilution 1.0 ug/ml.

Anti-ETS1 / ETS-1 Antibody (aa151-244) - LS-C311456 from LifeSpan Bioscience

Prices $250.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ETS1 / ETS-1 Antibody (phospho-Thr38) - LS-C342104 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ETS1 / ETS-1 Antibody (Ala32) - LS-C175893 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of ETS1 (A32) pAb in paraffin-embedded human hepatic carcinoma tissue.

Anti-ETS1 / ETS-1 Antibody (clone 10D2) - LS-C109133 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 10D2
IHC of paraffin-embedded human brain tissue (A) and breast tumor (B) using ETS1 mouse monoclonal antibody.

Anti-ETS1 / ETS-1 Antibody (phospho-Thr38) - LS-C198939 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human breast carcinoma, using ETS1 (Phospho-Thr38) Antibody. The sample on the right was incubated with synthetic peptide.

Anti-ETS1 / ETS-1 Antibody (clone 2G10) - LS-C197162 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G10
Immunofluorescence of monoclonal antibody to ETS1 on HeLa cell . [antibody concentration 10 ug/ml]

Anti-ETS1 / ETS-1 Antibody (clone ETS1B8D7) - LS-C342336 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone ETS1B8D7
Western blot analysis of immunized recombinant protein, using anti-ETS1 monoclonal antibody.

Anti-ETS1 / ETS-1 Antibody (aa43-70) - LS-C167843 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Confocal immunofluorescent of ETS1 Antibody with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
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