ETS1

Gene Symbol ETS1
Entrez Gene 2113
Alt Symbol ETS-1, EWSR2, p54
Species Human
Gene Type protein-coding
Description v-ets avian erythroblastosis virus E26 oncogene homolog 1
Other Description Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1|protein C-ets-1|v-ets avian erythroblastosis virus E2 oncogene homolog 1
Swissprots Q16080 P14921 A9UL17 F5GYX9 Q96AC5 Q14278 Q6N087
Accessions AAA52409 EAW67709 EAW67710 EAW67711 EAW67712 P14921 AK001630 AK291840 BAF84529 AK301405 BAG62940 AL832693 AY943926 AAY19514 BC017314 AAH17314 BG035366 BM468663 BP365215 BT019452 AAV38259 BT019453 AAV38260 BX640634 CAE45783 CA407336 CR542254 CAG47050 J04101 AAA52410 S53284 S67063 AAB28747 S87905 X14798 CAA32903 XM_011542649 XP_011540951 XM_011542650 XP_011540952 XM_011542651 XP_011540953 XM_011542652 XP_011540954 NM_001143820 NP_001137292 NM_001162422 NP_001155894 NM_005238 NP_005229
Function Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion. {ECO:0000269|PubMed:10698492, ECO:0000269|PubMed:11909962, ECO:0000269|PubMed:15247905, ECO:0000269|PubMed:15592518}.
Subcellular Location Cytoplasm. Nucleus. Note=Delocalizes from nucleus to cytoplasm when coexpressed with isoform Ets-1 p27.
Tissue Specificity Highly expressed within lymphoid cells. Isoforms c-ETS-1A and Ets-1 p27 are both detected in all fetal tissues tested, but vary with tissue type in adult tissues. None is detected in brain or kidney. {ECO:0000269|PubMed:19377509, ECO:0000269|PubMed:20378371}.
Top Pathways Renal cell carcinoma, HTLV-I infection, Dorso-ventral axis formation

ETS1 overexpression lysate - LY428365 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

ETS1 293 Cell Lysate - 401454 from ABBIOTEC

Category Cell Lysate
Prices $672.00
Sizes 100 µg

Ets-1 Overexpression Lysate (Native) - NBL1-10355 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: ETS1 Overexpression Lysate (Adult Normal) [NBL1-10355] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ETS1.

ETS1 Over-expression Lysate Product - GWB-CA8D50 from Genway Biotech

Category Cell Lysate
Prices $756.00
Sizes 100 µg
Species Human

Ets-1 Overexpression Lysate (Denatured) - H00002113-T02 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human ETS1 Knockdown Stable Cell Line - CSC-DC005101 from Creative biogene

Category Cell Line
Species Human
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