KDM2B

Gene Symbol	KDM2B
Entrez Gene	84678
Alt Symbol	CXXC2, FBXL10, Fbl10, JHDM1B, PCCX2
Species	Human
Gene Type	protein-coding
Description	lysine (K)-specific demethylase 2B
Other Description	CXXC-type zinc finger protein 2|F-box and leucine-rich repeat protein 10|F-box protein FBL10|F-box/LRR-repeat protein 10|JEMMA (Jumonji domain, EMSY-interactor, methyltransferase motif) protein|[Histone-H3]-lysine-36 demethylase 1B|jmjC domain-containing histone demethylation protein 1B|jumonji C domain-containing histone demethylase 1B|lysine-specific demethylase 2B|protein-containing CXXC domain 2
Swissprots	Q96T03 A8MRS1 Q8NCI2 Q9NS96 Q96HC7 Q9UF75 Q96SL0 Q1RLM7 Q8NHM5
Accessions	EAW98266 EAW98267 EAW98268 Q8NHM5 AA504464 AB031230 BAA97672 AJ459424 CAD30700 AK027440 BAB55112 AK027692 BAB55301 AK074718 BAC11159 AK097933 AK127328 BAG54483 AK299827 BAG61696 AK316470 BAH14841 AL133572 CAB63721 BC008735 AAH08735 BC028612 BC115379 AAI15380 BC115380 AAI15381 BX648928 CA430876 XM_005253955 XP_005254012 XM_005253956 XP_005254013 XM_005253961 XP_005254018 XM_011538860 XP_011537162 XM_011538861 XP_011537163 XM_011538862 XP_011537164 XM_011538863 XP_011537165 XM_011538864 XP_011537166 XM_011538865 XP_011537167 XM_011538866 XP_011537168 XM_011538867 XP_011537169 XM_011538868 XP_011537170 XM_011538869 XP_011537171 XM_011538870 XP_011537172 XM_011538871 XP_011537173 XM_011538872 XP_011537174 XM_011538873 XP_011537175 XM_011538874 XP_011537176 XM_011538875 XP_011537177 XR_944787 NM_001005366 NP_001005366 NM_032590 NP_115979
Function	Histone demethylase that demethylates 'Lys-4' and 'Lys- 36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' and dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. {ECO:0000269|PubMed:16362057, ECO:0000269|PubMed:17994099}.
Subcellular Location	Nucleus, nucleolus {ECO:0000269|PubMed:17994099}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FBL10 (S-15) - sc-69477 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-KDM2B antibody - ab5199 from Abcam Prices $387.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-KDM2B antibody - C-terminal - ab137547 from Abcam Prices $376.00 Sizes 50 µl Host Rabbit Clonality Polyclonal

Anti-KDM2B antibody - N-terminal - ab189781 from Abcam Prices $376.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-KDM2B / FBXL10 Antibody (C-Terminus) IHC-plus™ - LS-B5649 from LifeSpan Bioscience Prices $450.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-KDM2B / FBXL10 Antibody (aa1-30, AP) - LS-C257088 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KDM2B / FBXL10 Antibody (aa1-30, APC) - LS-C257089 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KDM2B / FBXL10 Antibody (aa1-30, Biotin) - LS-C257090 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KDM2B / FBXL10 Antibody (aa1-30, FITC) - LS-C257091 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KDM2B / FBXL10 Antibody (aa1-30, Azide-free, HRP) - LS-C257092 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KDM2B / FBXL10 Antibody (aa1-30, PE) - LS-C257095 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KDM2B / FBXL10 Antibody (aa1-30) - LS-C166069 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-KDM2B / FBXL10 Antibody (C-Terminus, APC) - LS-C278703 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KDM2B / FBXL10 Antibody (C-Terminus, FITC) - LS-C278705 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KDM2B / FBXL10 Antibody (C-Terminus, AP) - LS-C278704 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KDM2B / FBXL10 Antibody (C-Terminus, Azide-free, HRP) - LS-C278707 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KDM2B / FBXL10 Antibody (C-Terminus, Biotin) - LS-C278706 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KDM2B / FBXL10 Antibody (C-Terminus, PE) - LS-C278709 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KDM2B / FBXL10 Antibody (N-Terminus, AP) - LS-C278708 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KDM2B / FBXL10 Antibody (N-Terminus, APC) - LS-C278710 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KDM2B / FBXL10 Antibody (N-Terminus, Biotin) - LS-C278711 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KDM2B / FBXL10 Antibody (N-Terminus, FITC) - LS-C278712 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KDM2B / FBXL10 Antibody (N-Terminus, PE) - LS-C278714 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KDM2B / FBXL10 Antibody (aa1-30) - LS-C321303 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KDM2B / FBXL10 Antibody (aa457-556) - LS-C308613 from LifeSpan Bioscience Prices $455.00 Sizes 100 µg Host Mouse Clonality Monoclonal

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