Gene Symbol | Taok3 |
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Entrez Gene | 330177 |
Alt Symbol | 2900006A08Rik, A130052D22, A430105I05Rik |
Species | Mouse |
Gene Type | protein-coding |
Description | TAO kinase 3 |
Other Description | serine/threonine-protein kinase TAO3|thousand and one amino acid protein 3 |
Swissprots | Q3V3B3 Q8BYC6 |
Accessions | Q8BYC6 AA182196 AK013486 AK037817 AK039665 BAE20549 AK040531 BAC30618 AK042181 BAE20625 AK138024 AK155208 AK170794 AK171353 BAE42407 AK188887 AK217809 BC158072 AAI58073 BM225493 BY201674 CK625948 XM_006530385 XP_006530448 XM_011248219 XP_011246521 XM_011248220 XP_011246522 XM_011248221 XP_011246523 NM_001081308 NP_001074777 NM_001199685 NP_001186614 NM_183306 NP_899129 |
Function | Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress- activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF) (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Top Pathways | MAPK signaling pathway |
Anti-JIK antibody - N-terminal - ab172946 from Abcam
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ANTI-MOUSE TAOK3 (N-TERM) antibody produced in rabbit - SAB1301977 from Sigma-Aldrich
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Mouse-Taok3-Antibody-N-term - AP17319a from Abgent, a WuXi AppTec company
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Mouse Taok3 Antibody - N-terminal region (OAAB12750) - OAAB12750 from Aviva Systems Biology
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Mouse Taok3 Antibody - abx029445 from Abbexa
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TAOK3, Monoclonal Antibody - MBS642620 from MyBioSource
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TAOK3, Monoclonal Antibody - MBS645801 from MyBioSource
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Anti-TAOK3 (aa 256-284) polyclonal antibody - DPABH-27559 from Creative Diagnostics
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TAOK3, Polyclonal Antibody - MBS649513 from MyBioSource
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Taok3, Polyclonal Antibody - MBS6012263 from MyBioSource
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JIK antibody - 70R-50983 from Fitzgerald
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Taok3, Polyclonal Antibody - MBS9210155 from MyBioSource
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anti-JIK antibody - ARG20247 from Arigo Biolaboratories
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Taok3 antibody - orb164562 from Biorbyt
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Mouse Taok3 Antibody - 59-112 from ProSci
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