Gene Symbol | Taok3 |
---|---|
Entrez Gene | 330177 |
Alt Symbol | 2900006A08Rik, A130052D22, A430105I05Rik |
Species | Mouse |
Gene Type | protein-coding |
Description | TAO kinase 3 |
Other Description | serine/threonine-protein kinase TAO3|thousand and one amino acid protein 3 |
Swissprots | Q3V3B3 Q8BYC6 |
Accessions | Q8BYC6 AA182196 AK013486 AK037817 AK039665 BAE20549 AK040531 BAC30618 AK042181 BAE20625 AK138024 AK155208 AK170794 AK171353 BAE42407 AK188887 AK217809 BC158072 AAI58073 BM225493 BY201674 CK625948 XM_006530385 XP_006530448 XM_011248219 XP_011246521 XM_011248220 XP_011246522 XM_011248221 XP_011246523 NM_001081308 NP_001074777 NM_001199685 NP_001186614 NM_183306 NP_899129 |
Function | Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress- activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF) (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Top Pathways | MAPK signaling pathway |
Taok3 CRISPR/Cas9 KO Plasmid (m) - sc-435996 from Santa Cruz Biotechnology
|
||||||||
Taok3 HDR Plasmid (m) - sc-435996-HDR from Santa Cruz Biotechnology
|
||||||||
Taok3 Double Nickase Plasmid (m) - sc-435996-NIC from Santa Cruz Biotechnology
|
||||||||
Taok3 Double Nickase Plasmid (m2) - sc-435996-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Taok3 CRISPR Activation Plasmid (m) - sc-435996-ACT from Santa Cruz Biotechnology
|
||||||||
Taok3 CRISPR Activation Plasmid (m2) - sc-435996-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Taok3 Lentiviral Activation Particles (m) - sc-435996-LAC from Santa Cruz Biotechnology
|
||||||||
Taok3 Lentiviral Activation Particles (m2) - sc-435996-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Taok3 siRNA (m) - sc-154067 from Santa Cruz Biotechnology
|
||||||||
Taok3 shRNA Plasmid (m) - sc-154067-SH from Santa Cruz Biotechnology
|
||||||||
Taok3 shRNA (m) Lentiviral Particles - sc-154067-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EMU152661 from Sigma-Aldrich
|
||||||||
MISSION® Long Non-Coding esiRNA - EMNC003011 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN42474 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND42474 from Sigma-Aldrich
|
||||||||
TAOK3 siRNA (Mouse) - CRN4623 from Cohesion Biosciences
|
||||||||
TAOK3 - MBS8228152 from MyBioSource
|
||||||||
shRNA set against Mouse TAOK3 (NM_001081308.2) - SHH423004 from Creative biogene
|
||||||||
Mouse TAOK3 siRNA - orb294098 from Biorbyt
|
||||||||
TAOK3 shRNA Plasmid (Mouse) - CHN4623 from Cohesion Biosciences
|