HMGCLL1

Gene Symbol HMGCLL1
Entrez Gene 54511
Alt Symbol bA418P12.1, er-cHL
Species Human
Gene Type protein-coding
Description 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
Other Description 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic|3-hydroxymethyl-3-methylglutaryl-CoA lyase-like protein 1|3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1|endoplasmic reticulum 3-hydroxymethyl-3-methylglutaryl-CoA lyase|probable 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2
Swissprots B3KNV0 F8W793 B7Z1S7 B1AQ42 Q8TB92 Q6ZSA9
Accessions EAX04442 EAX04443 EAX04444 EAX04445 Q8TB92 AF131827 AAD20054 AK055075 BAG51462 AK127587 BAC87045 AK293856 BAH11613 AK294210 BAH11698 AK297191 BAH12520 AL137605 CAB70838 BC024194 AAH24194 DA508472 DB179645 HQ447228 ADQ31715 XM_011514700 XP_011513002 XM_011514701 XP_011513003 NM_001042406 NP_001035865 NM_001287741 NP_001274670 NM_001287746 NP_001274675 NM_001287753 NP_001274682 NM_019036 NP_061909 NR_109867 NR_109869
Function Non-mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy- 3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis, the products of which support energy production in nonhepatic animal tissues. {ECO:0000269|PubMed:22847177, ECO:0000269|PubMed:22865860}.
Subcellular Location Cytoplasm, cytosol. Endoplasmic reticulum membrane; Peripheral membrane protein.
Top Pathways Peroxisome, Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism

HMGCLL1 293 Cell Lysate - 409464 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

HMGCLL1 Overexpression Lysate (Native) - NBL1-11618 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: HMGCLL1 Overexpression Lysate (Adult Normal) [NBL1-11618] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for HMGCLL1.

HMGCLL1 Over-expression Lysate Product - GWB-FEAAE4 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human HMGCLL1 Knockdown Stable Cell Line - CSC-DC007121 from Creative biogene

Category Cell Line
Species Human
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