HMGCLL1

Gene Symbol HMGCLL1
Entrez Gene 54511
Alt Symbol bA418P12.1, er-cHL
Species Human
Gene Type protein-coding
Description 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
Other Description 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic|3-hydroxymethyl-3-methylglutaryl-CoA lyase-like protein 1|3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1|endoplasmic reticulum 3-hydroxymethyl-3-methylglutaryl-CoA lyase|probable 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2
Swissprots B3KNV0 F8W793 B7Z1S7 B1AQ42 Q8TB92 Q6ZSA9
Accessions EAX04442 EAX04443 EAX04444 EAX04445 Q8TB92 AF131827 AAD20054 AK055075 BAG51462 AK127587 BAC87045 AK293856 BAH11613 AK294210 BAH11698 AK297191 BAH12520 AL137605 CAB70838 BC024194 AAH24194 DA508472 DB179645 HQ447228 ADQ31715 XM_011514700 XP_011513002 XM_011514701 XP_011513003 NM_001042406 NP_001035865 NM_001287741 NP_001274670 NM_001287746 NP_001274675 NM_001287753 NP_001274682 NM_019036 NP_061909 NR_109867 NR_109869
Function Non-mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy- 3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis, the products of which support energy production in nonhepatic animal tissues. {ECO:0000269|PubMed:22847177, ECO:0000269|PubMed:22865860}.
Subcellular Location Cytoplasm, cytosol. Endoplasmic reticulum membrane; Peripheral membrane protein.
Top Pathways Peroxisome, Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism

HMGCLL1 CRISPR/Cas9 KO Plasmid (h) - sc-412295 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HMGCLL1 HDR Plasmid (h) - sc-412295-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HMGCLL1 Double Nickase Plasmid (h) - sc-412295-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HMGCLL1 Double Nickase Plasmid (h2) - sc-412295-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HMGCLL1 CRISPR Activation Plasmid (h) - sc-412295-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HMGCLL1 CRISPR Activation Plasmid (h2) - sc-412295-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HMGCLL1 Lentiviral Activation Particles (h) - sc-412295-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HMGCLL1 Lentiviral Activation Particles (h2) - sc-412295-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HMGCLL1 siRNA (h) - sc-95556 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HMGCLL1 shRNA Plasmid (h) - sc-95556-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HMGCLL1 shRNA (h) Lentiviral Particles - sc-95556-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU099401 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10165 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10165 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08682 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08682

HMGCLL1 siRNA (Human) - CRJ0105 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HMGCLL1 - MBS8232852 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HMGCLL1 (NM_019036.2) - SHH313361 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human HMGCLL1(NM_001042406.1) - SHH125291 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human HMGCLL1(NM_019036.2) - SHH125327 from Creative biogene

Category siRNA
Species Reactivities Human

HMGCLL1 shRNA Plasmid (Human) - CHJ0105 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HMGCLL1 miRNA 3'UTR clone - MiUTR1H-04604 from Creative biogene

Species Reactivities Human

HMGCLL1 miRNA 3'UTR clone - MiUTR1H-04605 from Creative biogene

Species Reactivities Human
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