Vcl

Gene Symbol Vcl
Entrez Gene 305679
Alt Symbol -
Species Rat
Gene Type protein-coding
Description vinculin
Other Description metavinculin {ECO:0000250|UniProtKB:P18206}|vcl {ECO:0000250|UniProtKB:P18206}|vinculin {ECO:0000250|UniProtKB:P18206}
Swissprots P85972 A6KKR4
Accessions EDL86257 EDL86258 P85972 FQ229885 XM_006251639 XP_006251701 NM_001107248 NP_001100718
Function Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell- surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000269|PubMed:19343716}. Cell junction, adherens junction {ECO:0000250|UniProtKB:P18206}. Cell membrane {ECO:0000250|UniProtKB:P18206}; Peripheral membrane protein {ECO:0000250|UniProtKB:P18206}; Cytoplasmic side {ECO:0000250|UniProtKB:P18206}. Cell junction, focal adhesion {ECO:0000250}. Note=Cytoplasmic face of adhesion plaques. Recruitment to cell-cell junctions occurs in a myosin II-dependent manner. Interaction with CTNNB1 is necessary for its localization to the cell-cell junctions. Colocalizes with LIMD1 in the focal adhesions (By similarity). {ECO:0000250}.
Top Pathways Adherens junction, Focal adhesion, Leukocyte transendothelial migration, Bacterial invasion of epithelial cells, Amoebiasis

Vinculin, Rat, ELISA Kit - E02V0025 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t
Sensitivity 1.0ng/ml
Range 5.0-100ng/ml

Vinculin, Vcl, Rat, ELISA Kit - E1839r from ARP American Research Products

Category ELISA Kit
Prices $596.00
Sizes 96 t

Rat VCL ELISA Kit - RV0032 from NeoScientific

Category ELISA Kit
Prices $495.00
Sizes 96 t

Rat Vinculin ELISA - E02V0025 from BlueGene Biotech

Category ELISA Kit

Rat Vcl ELISA Kit - E102568 from Biobool

Category ELISA Kit

VCL ELISA Kit (Rat) (OKEH06096) - OKEH06096 from Aviva Systems Biology

Category ELISA Kit
Prices $440.00
Sizes 96 wells
Sensitivity 0.78 ng/mL
Range 1.56-100 ng/mL

Rat VCL ELISA Kit - ERV0032 from ABclonal

Category ELISA Kit
Prices $495.00
Sizes 96 t

Rat Vinculin ELISA Kit - EK4010 from Signalway Antibody

Category ELISA Kit
Prices $599.00
Sizes 1x96t
Sensitivity less than 0.23ng/mL
Range 0.312-20 ng/mL

Vinculin, ELISA Kit - MBS2880562 from MyBioSource

Category ELISA Kit
Prices $380.00, $500.00, $2,170.00, $3,840.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Vinculin, ELISA Kit - MBS9427840 from MyBioSource

Category ELISA Kit
Prices $555.00
Sizes 96 tests
Range 1.56-100 ng/mL
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