Slc29a4

Gene Symbol Slc29a4
Entrez Gene 243328
Alt Symbol ENT4, mPMAT
Species Mouse
Gene Type protein-coding
Description solute carrier family 29 (nucleoside transporters), member 4
Other Description equilibrative nucleoside transporter 4|solute carrier family 29 member 4
Swissprots Q8R139
Accessions Q8R139 BC025599 AAH25599 BY727407 XM_006504706 XP_006504769 XM_006504707 XP_006504770 XM_011240982 XP_011239284 NM_146257 NP_666369
Function Functions as a polyspecific organic cation transporter, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, dopamine, norepinephrine and epinephrine. May play a role in regulating central nervous system homeostasis of monoamine neurotransmitters. May be involved in luminal transport of organic cations in the kidney and seems to use luminal proton gradient to drive organic cation reabsorptprev reabsorption. Does not seem to transport nucleoside and nucleoside analogs such as uridine, cytidine, thymidine, adenosine, inosine, guanosine, and azidothymidine. In (PubMed:16873718) adenosine is efficiently transported but in a fashion highly sensitive to extracellular pH, with maximal activity in the pH range 5.5 to 6.5. Glu-206 is essential for the cation selectivity and may function as the charge sensor for cationic substrates. Transport is chloride and sodium-independent but appears to be sens
Subcellular Location Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Apical cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Located to the plasma membranes of ventricular myocytes and vascular endothelial cells. Targeted to the apical membranes of differentiated kidney epithelial cells (By similarity). {ECO:0000250}.
Tissue Specificity Expressed in heart. {ECO:0000269|PubMed:16873718}.

Anti-SLC29A4 Antibody (Internal) IHC-plus™ - LS-B12119 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-SLC29A4 Antibody (C-Terminus, AP) - LS-C245373 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A4 Antibody (C-Terminus, APC) - LS-C245375 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A4 Antibody (C-Terminus, FITC) - LS-C245376 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A4 Antibody (C-Terminus, Biotin) - LS-C245377 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A4 Antibody (N-Terminus, APC) - LS-C245378 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A4 Antibody (N-Terminus, AP) - LS-C245379 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A4 Antibody (C-Terminus, PE) - LS-C245380 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A4 Antibody (N-Terminus, Biotin) - LS-C245381 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A4 Antibody (N-Terminus, PE) - LS-C245383 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A4 Antibody (N-Terminus, FITC) - LS-C245382 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A4 Antibody (C-Terminus, Azide-free, HRP) - LS-C247770 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A4 Antibody (N-Terminus, Azide-free, HRP) - LS-C247771 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A4 Antibody (N-Terminus) - LS-C328278 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A4 Antibody (N-Terminus) - LS-C328279 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC29A4 Antibody (aa283-346, Azide-free) - LS-C328721 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-SLC29A4 Antibody (aa452-481) - LS-C96643 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of PMAT(Slc29a4) (arrow) using rabbit polyclonal PMAT(Slc29a4) Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PMAT(Slc29a4) gene (Lane 2) (Origene Technologies).

Anti-SLC29A4 Antibody (aa39-69) - LS-C96642 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with PMAT(Slc29a4) Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-Phospho-PMAT-Y198 antibody produced in rabbit - SAB1300725 from Sigma-Aldrich

Prices $291.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Dot blot analysis of Anti-Phospho-PMAT-Y198 Antibody: <B>Cat No. SAB1300725</B>: Anti-Phospho-PMAT-Y198 Antibody with Phospho-peptide or Non Phospho-peptide at 0.5 μg/mL.

ANTI-PMAT(SLC29A4)(N-TERMINAL) antibody produced in rabbit - SAB1307001 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PMAT(Slc29a4) (N-term): <B>Cat. No. SAB1307001</B>: Western blot analysis of Anti-PMAT(Slc29a4) Antibody (N-term) in HepG2 cell line lysates (35 μg/lane).

ANTI-PMAT(SLC29A4)(C-TERMINAL) antibody produced in rabbit - SAB1306782 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PMAT(Slc29a4) (C-term): <B>Cat. No. SAB1306782</B>: Western blot analysis of PMAT(Slc29a4) (arrow) using Rabbit polyclonal PMAT(Slc29a4) (C-term) .

Anti-PMAT(Slc29a4) (N-term) antibody produced in rabbit - SAB1300519 from Sigma-Aldrich

Prices $291.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PMAT(SLC29A4) (N-term) Antibody: <B>Cat. No. SAB1300519</B>: PMAT in human breast carcinoma tissue with Anti-PMAT(SLC29A4) (N-term) Antibody at 40 μg/mL.

Slc29a4 Antibody - N-terminal region (OAAB00899) - OAAB00899 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Slc29a4 Antibody - C-terminal region (OAAB00900) - OAAB00900 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

PMATSlc29a4-Antibody-C-term - AP1087b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of PMAT(Slc29a4) (arrow) using rabbit polyclonal PMAT(Slc29a4) Antibody (C-term) (Cat.#AP1087b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PMAT(Slc29a4) gene (Lane 2) (Origene Technologies).
Search more