Gene Symbol | Ace2 |
---|---|
Entrez Gene | 70008 |
Alt Symbol | 2010305L05Rik |
Species | Mouse |
Gene Type | protein-coding |
Description | angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 |
Other Description | ACE-related carboxypeptidase|angiotensin I converting enzyme 2|angiotensin-converting enzyme 2 |
Swissprots | Q8R0I0 Q99N70 Q99N71 |
Accessions | EDL40761 Q8R0I0 AB053181 BAB40431 AB053182 BAB40432 AI115946 AK008530 BAB25723 AK135357 BAE22502 AK141604 BAE24759 BC026801 AAH26801 BY722909 EF408739 ABN80105 EF408740 ABN80106 GQ262785 ACT66269 NM_001130513 NP_001123985 NM_027286 NP_081562 |
Function | Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin- 13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. May have a protective role in acute lung injury. {ECO:0000269|PubMed:12075344, ECO:0000269|PubMed:12967627, ECO:0000269|PubMed:16001071}. |
Subcellular Location | Processed angiotensin-converting enzyme 2: Secreted {ECO:0000250}. |
Tissue Specificity | Expressed in heart, kidney and forebrain (at protein level). Ubiquitously expressed, with highest levels in ileum, kidney and lung. In lung, expressed on vascular endothelial and airway epithelial cells. {ECO:0000269|PubMed:12487024, ECO:0000269|PubMed:15949646, ECO:0000269|PubMed:16001071}. |
Top Pathways | Protein digestion and absorption, Renin-angiotensin system |
ACE2 (D-20) - sc-21834 from Santa Cruz Biotechnology
|
||||||||||
ACE-2 Antibody [Unconjugated] - AF3437 from Novus Biologicals
|
||||||||||
ACE-2 Antibody (460502) - MAB3437 from Novus Biologicals
|
||||||||||
ACE2 Antibody - abx103398 from Abbexa
|
||||||||||
ACE2 antibody - PAB5861 from Acris Antibodies
|
||||||||||
Rabbit Anti-Human ACE2 - DS-PB-02476 from RayBiotech
|
||||||||||
Anti-Angiotensin I Converting Enzyme 2 (ACE2) - 20-4206 from ARP American Research Products
|
||||||||||
Angiotensin I Converting Enzyme 2 (ACE2), Polyclonal Antibody - MBS2003493 from MyBioSource
|
||||||||||
Angiotensin I Converting Enzyme 2 (ACE2), Polyclonal Antibody - MBS2014276 from MyBioSource
|
||||||||||
Angiotensin I Converting Enzyme 2 (ACE2), Polyclonal Antibody - MBS2004634 from MyBioSource
|
||||||||||
Anti-ACE2 (N-terminal) polyclonal antibody - DPAB-DC3039 from Creative Diagnostics
|
||||||||||
Polyclonal Antibody to Angiotensin I Converting Enzyme 2 (ACE2) - PAB886Mu01 from Cloud-clone
|
||||||||||
Polyclonal Antibody to Angiotensin I Converting Enzyme 2 (ACE2) - PAB886Mu02 from Cloud-clone
|
||||||||||
Biotin-Linked Antibody to Angiotensin I Converting Enzyme 2 (ACE2) - PAB886Mu71 from Cloud-clone
|
||||||||||
FITC-Linked Antibody to Angiotensin I Converting Enzyme 2 (ACE2) - PAB886Mu81 from Cloud-clone
|
||||||||||
Anti-ACE2 Antibody A00756 - A00756 from Boster Bio
|
||||||||||
Angiotensin I Converting Enzyme 2 (ACE2) Polyclonal Antibody - CAU25122 from Biomatik
|