LAS1L

Gene Symbol LAS1L
Entrez Gene 81887
Alt Symbol Las1-like, dJ475B7.2
Species Human
Gene Type protein-coding
Description LAS1-like (S. cerevisiae)
Other Description protein LAS1 homolog|ribosomal biogenesis protein LAS1L
Swissprots A9X410 Q5JXQ0 Q8TEN5 Q9H9V5 Q9Y4W2
Accessions EAX05401 EAX05402 EAX05403 EAX05404 Q9Y4W2 AF116730 AAO15306 AK022587 BAB14114 AK054695 AK054817 BAG51428 AK074087 BAB84913 AK097383 BAG53459 AK125760 BAG54243 AK127207 AK225059 AK295591 BAH12117 BC014545 AAH14545 BC018610 AAH18610 BC019302 AAH19302 DA619280 DQ323624 ABD39127 DQ323625 ABD39128 DQ323626 ABD39129 XM_005262301 XP_005262358 XM_005262304 XP_005262361 XM_005262305 XP_005262362 XM_005262306 XP_005262363 XM_005262307 XP_005262364 XM_011531045 XP_011529347 XM_011531046 XP_011529348 XR_244504 XR_430522 XR_938411 XR_938412 NM_001170649 NP_001164120 NM_001170650 NP_001164121 NM_031206 NP_112483
Function Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. {ECO:0000269|PubMed:20647540, ECO:0000269|PubMed:22872859}.
Subcellular Location Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:20647540}. Nucleus, nucleoplasm {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions (By similarity). Localizes mainly to the granular component, the region implicated in the later steps of rRNA processing and subunit assembly and export. {ECO:0000250}.

Human LAS1L full length protein - ab164379 from Abcam

Category Protein
Source Wheat germ
Species Human
ab164379 on a 12.5% SDS-PAGE stained with Coomassie Blue.

LAS1L Antibody Blocking Peptide - LS-E4955 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

LAS1L Antibody Blocking Peptide - LS-E12308 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human LAS1L Protein - H00081887-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human

LAS1L-Antibody-C-term-Blocking-Peptide - BP17345b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

LAS1L - H00081887-P01 from Acris Antibodies

Category Protein
Prices $310.00
Sizes 2 µg
Species Human

LAS1L fusion protein - Ag8732 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

LAS1L fusion protein - Ag8881 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Human LAS1L, GST-tagged - LAS1L-511H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human Ribosomal biogenesis protein LAS1L(LAS1L) - CSB-YP897285HU CSB-EP897285HU CSB-BP897285HU CSB-MP897285HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

LAS1L Recombinant Protein Antigen - NBP2-38921PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

LAS1L Antibody - SH-A13250 from Novatein Biosciences

Prices $315.00
Sizes 100 µl
Species Human, Mouse, Rat

LAS1L Peptide, Human - M34GP08556H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Ribosomal biogenesis protein LAS1L (LAS1L), Recombinant Protein - MBS1367684 from MyBioSource

Category Protein
Prices $1,545.00, $1,545.00, $1,775.00, $1,775.00, $2,655.00, $2,655.00, $3,095.00, $3,095.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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