Gapdh

Gene Symbol Gapdh
Entrez Gene 24383
Alt Symbol BARS-38, Gapd
Species Rat
Gene Type protein-coding
Description glyceraldehyde-3-phosphate dehydrogenase
Other Description 38 kDa BFA-dependent ADP-ribosylation substrate|peptidyl-cysteine S-nitrosylase GAPDH
Swissprots Q9QWU4 P09328 Q5M916 P04797
Accessions EDM01863 P04797 AB017801 BAB11748 BC059110 AAH59110 BC087743 AAH87743 DQ403053 ABD77186 M11561 AAA41795 M17701 AAA41193 M29341 AAA40814 U75401 AAB19105 X02231 CAA26150 NM_017008 NP_058704
Function Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3- phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S- nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in infl
Subcellular Location Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Nucleus. Note=Translocates to the nucleus following S- nitrosylation and interaction with SIAH1, which contains a nuclear localization signal. Colocalizes with CHP1 to small punctate structures along the microtubules tracks.
Tissue Specificity High levels in skeletal muscle and heart, low levels in liver, brain, and kidney. {ECO:0000269|PubMed:6548307}.
Top Pathways Glycolysis / Gluconeogenesis, Alzheimer's disease, Biosynthesis of amino acids, Carbon metabolism

GAPDH Antibody - NBP2-22456 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: GAPDH Antibody [NBP2-22456] - Rat heart protein extract.

GAPDH Antibody (OAAB17810) - OAAB17810 from Aviva Systems Biology

Prices $320.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-GAPDH3E12-antibody - AP50812 from Abgent, a WuXi AppTec company

Prices $295.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Western blot analysis of lysate from human skeletal muscle tissue lysate,using Anti-GAPDH(3E12) antibody(AP50812). AP50812 was diluted at 1:1000. A goat anti-mouse IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.

GAPDH antibody - AP10096PU-N from Acris Antibodies

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Sheep Anti-Human GAPDH - 129-10311 from RayBiotech

Host Sheep

GAPDH, Polyclonal Antibody - MBS857640 from MyBioSource

Prices $175.00, $215.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

GAPDH, Polyclonal Antibody - MBS448046 from MyBioSource

Prices $410.00, $560.00
Sizes 400 µg, 1 mg
Host Goat
Clonality Polyclonal

GAPDH, Polyclonal Antibody - MBS435011 from MyBioSource

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GAPDH, Polyclonal Antibody - MBS448069 from MyBioSource

Prices $410.00
Sizes 400 µg
Host Goat
Clonality Polyclonal

GAPDH, Monoclonal Antibody - MBS330060 from MyBioSource

Prices $210.00, $775.00
Sizes 100 µg, 1 mg
Host Mouse
Clonality Monoclonal
Clone GH. H8

GAPDH, Monoclonal Antibody - MBS533386 from MyBioSource

Prices $210.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone GA1R

GAPDH, Monoclonal Antibody - MBS533395 from MyBioSource

Prices $310.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1A10

GAPDH, Monoclonal Antibody - MBS850599 from MyBioSource

Prices $175.00, $215.00
Sizes 50 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D4

GAPDH, Monoclonal Antibody - MBS462002 from MyBioSource

Prices $285.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6C5

GAPDH, Monoclonal Antibody - MBS525009 from MyBioSource

Prices $195.00, $245.00, $325.00, $805.00
Sizes 50 µg, 100 µg, 200 µg, 1 mg
Host Mouse
Clonality Monoclonal
Clone GA1R

Anti-GAPDH polyclonal antibody - DPAB-DC1152 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

GAPDH, Polyclonal Antibody - MBS440117 from MyBioSource

Prices $240.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

GAPDH, Polyclonal Antibody - MBS540232 from MyBioSource

Prices $425.00
Sizes 0.1 mg affinity-purified
Host Rabbit
Clonality Polyclonal

GAPDH (2A8), Monoclonal Antibody - MBS435076 from MyBioSource

Prices $195.00, $255.00, $330.00, $1,110.00
Sizes 50 µl, 100 µl, 200 µl, 1 ml
Clonality Monoclonal

GAPDH (3B3), Monoclonal Antibody - MBS435077 from MyBioSource

Prices $195.00, $255.00, $330.00, $1,110.00
Sizes 50 µl, 100 µl, 200 µl, 1 ml
Clonality Monoclonal

Glyceraldehyde-3-Phosphate Dehydrogenase, Monoclonal Antibody - MBS140362 from MyBioSource

Prices $140.00, $205.00, $505.00
Sizes 5 µg, 20 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone PAT8G4AT

GAPDH (3E12), Monoclonal Antibody - MBS9200326 from MyBioSource

Prices $340.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

GAPDH antibody - orb38656 from Biorbyt

Prices $187.00, $383.00
Sizes 80 μl (Trial size), 400 μl
Host Rabbit
Clonality Polyclonal
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