TPP1

Gene Symbol	TPP1
Entrez Gene	1200
Alt Symbol	CLN2, GIG1, LPIC, SCAR7, TPP-1
Species	Human
Gene Type	protein-coding
Description	tripeptidyl peptidase I
Other Description	cell growth-inhibiting gene 1 protein|growth-inhibiting protein 1|lysosomal pepstatin insensitive protease|tripeptidyl aminopeptidase|tripeptidyl-peptidase 1
Swissprots	Q71JP6 Q5JAK6 Q96C37 O14773 Q6UX56 Q53HT1
Accessions	AAC98480 CAH05560 EAW68685 EAW68686 O14773 AF017456 AAB80725 AI023962 AK222499 BAD96219 AK222538 BAD96258 AK293518 BAG57000 AK293741 BAG57164 AK295801 BAG58620 AK299703 BAG61604 AK300998 BAG62617 AK303323 BAG64389 AK312388 BAG35305 AY268890 AAQ72732 AY358502 AAQ88866 BC014863 AAH14863 BP279860 BP287220 DQ891682 ABM82608 DQ894867 ABM85793 NM_000391 NP_000382
Function	Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus (By similarity). {ECO:0000250}.
Subcellular Location	Lysosome. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue Specificity	Detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues.
Top Pathways	Lysosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TPP1 / CLN2 ELISA Kit (Sandwich ELISA) - LS-F7814 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Mouse TPP1 / CLN2 ELISA Kit (Sandwich ELISA) - LS-F8654 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.055 ng/ml Range 0.156-10 ng/ml

Tripeptidyl Peptidase I, TPP1, Human, ELISA Kit - E-EL-H1479 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Tripeptidyl Peptidase I (TPP1), Human, ELISA Kit - SEC828Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.063ng/mL Range 0.156-10ng/mL

Tripeptidyl-peptidase 1 (TPP1), Human, ELISA Kit - CSB-EL024113HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 3.12 pg/ml Range 12.5 pg/ml-800 pg/ml

Tripeptidyl Peptidase I, TPP1, Rabbit, ELISA Kit - E-EL-RB1314 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Tripeptidyl Peptidase I, TPP1, Chicken, ELISA Kit - E-EL-Ch2087 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Tripeptidyl Peptidase I, TPP1, Porcine, ELISA Kit - E-EL-P0996 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Tripeptidyl Peptidase I, TPP1, Sheep, ELISA Kit - E-EL-S0251 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Tripeptidyl Peptidase I, TPP1, Guinea Pig, ELISA Kit - E-EL-GP0531 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Tripeptidyl Peptidase I, TPP1, Monkey, ELISA Kit - E-EL-MK0968 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

TPP1 (Human) IP-WB Antibody Pair - H00001200-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

TPP1 (Human) Matched Antibody Pair - H00001200-AP51 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Custom Human Tripeptidyl-peptidase I ELISA - ELH-TPP1 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

TPP1, ELISA Kit - MBS2514705 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

TPP1, ELISA Kit - MBS2502706 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

TPP1, ELISA Kit - MBS2500919 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156--10ng/mL

TPP1, ELISA Kit - MBS2508926 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 37.5pg/mL Range 62.5-4000pg/mL

TPP1, ELISA Kit - MBS2512047 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

TPP1, ELISA Kit - MBS2511292 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

TPP1, ELISA Kit - MBS2512888 from MyBioSource Category ELISA Kit Prices $490.00, $585.00, $2,475.00, $4,360.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.469ng/mL Range 0.781-50ng/mL

tripeptidyl peptidase I, ELISA Kit - MBS912101 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 3.12 pg/ml Range 12.5 pg/ml-800 pg/ml

Tripeptidyl Peptidase I (TPP1), ELISA Kit - MBS9300561 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Tripeptidyl Peptidase I (TPP1), ELISA Kit - MBS2022105 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.063ng/mL. Range 0.156-10ng/mL

Tripeptidyl Peptidase I (TPP1), ELISA Kit - MBS2021113 from MyBioSource Category ELISA Kit Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.055ng/mL. Range 0.156-10ng/mL

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