TPP1

Gene Symbol	TPP1
Entrez Gene	1200
Alt Symbol	CLN2, GIG1, LPIC, SCAR7, TPP-1
Species	Human
Gene Type	protein-coding
Description	tripeptidyl peptidase I
Other Description	cell growth-inhibiting gene 1 protein|growth-inhibiting protein 1|lysosomal pepstatin insensitive protease|tripeptidyl aminopeptidase|tripeptidyl-peptidase 1
Swissprots	Q71JP6 Q5JAK6 Q96C37 O14773 Q6UX56 Q53HT1
Accessions	AAC98480 CAH05560 EAW68685 EAW68686 O14773 AF017456 AAB80725 AI023962 AK222499 BAD96219 AK222538 BAD96258 AK293518 BAG57000 AK293741 BAG57164 AK295801 BAG58620 AK299703 BAG61604 AK300998 BAG62617 AK303323 BAG64389 AK312388 BAG35305 AY268890 AAQ72732 AY358502 AAQ88866 BC014863 AAH14863 BP279860 BP287220 DQ891682 ABM82608 DQ894867 ABM85793 NM_000391 NP_000382
Function	Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus (By similarity). {ECO:0000250}.
Subcellular Location	Lysosome. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue Specificity	Detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues.
Top Pathways	Lysosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TPP1 full length protein - ab152286 from Abcam Category Protein Source Wheat germ Species Human

Human TPP1 protein fragment - ab152287 from Abcam Category Protein Source Wheat germ Species Human

TPP1-Antibody-N-term-Blocking-Peptide - BP17047a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TPP1 blocking peptide - GTX88372-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Dog, Bovine

Recombinant Human Tripeptidyl-peptidase I/TPP1, CF - 2237-SE-010 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Met1-Pro563, with a C-terminal 10-His tag

Human CLN2 protein - orb139798 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 10 μg, 20 μg Source Baculovirus-Insect Cells Species Human

TPP1 Peptide - AC21-1967-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Tripeptidyl-peptidase 1 (TPP1) - H00001200-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

Tripeptidyl-peptidase 1 (TPP1) - H00001200-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Tripeptidyl-peptidase 1 (TPP1) - H00001200-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TPP1 Peptide - 42-118P from ProSci Category Peptide Species Human

TPP1 fusion protein - ag3173 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human TPP1, His-tagged - TPP1-925H from Creative Biomart Category Protein Source NSO Cells Species Human

Recombinant Tripeptidyl Peptidase I (TPP1) - RPC828Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Tripeptidyl Peptidase I (TPP1) - RPC828Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Tripeptidyl Peptidase I (TPP1) - RPC828Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Tripeptidyl Peptidase I (TPP1) - RPC828Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Tripeptidyl aminopeptidase(tap) - CSB-YP700665FOI CSB-EP700665FOI CSB-BP700665FOI CSB-MP700665FOI from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Streptomyces

Recombinant Human Tripeptidyl-peptidase 1(TPP1) - CSB-YP024113HU CSB-EP024113HU CSB-BP024113HU CSB-MP024113HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Tripeptidyl-peptidase I/TPP1 Protein, CF - 2237-SE from R&D Systems Category Protein Prices $339.00 Sizes 10 µg Source Mouse myeloma cell line, NS0-derived Met1-Pro563, with a C-terminal 10-His tag Species Human

Tripeptidyl Peptidase I Protein (Recombinant) - abx166794 from Abbexa Category Protein Source Human Species Human

Tripeptidyl-peptidase 1 (TPP1) - TP721045 from Acris Antibodies Category Protein Prices $139.00 Sizes 10 µg Source HEK293 cells Species Human

CLN2/TPP1, Peptide - MBS425409 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Dog, Bovine

Recombinant Human TPP1 protein, His-tagged - TPP1-926H from Creative Biomart Category Protein Source Insect cells Species Human

TPP1 Antibody - SH-A16427 from Novatein Biosciences Prices $315.00 Sizes 100 µl Species Human, Mouse, Rat

Search more