FASLG

Gene Symbol	FASLG
Entrez Gene	356
Alt Symbol	ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6
Species	Human
Gene Type	protein-coding
Description	Fas ligand (TNF superfamily, member 6)
Other Description	CD95 ligand|apoptosis (APO-1) antigen ligand 1|apoptosis antigen ligand|fas antigen ligand|tumor necrosis factor ligand superfamily member 6
Swissprots	Q9BZP9 P48023
Accessions	AAB96632 AAC39768 ABK41922 BAA32542 CAX86839 CBX53895 CCA94585 EAW90935 EAW90936 P48023 AF288573 AAG60017 AK314874 BAG37389 AY225406 AAO43991 AY858799 AAX49569 BC017502 AAH17502 D38122 BAA07320 DA916336 DQ893466 ABM84392 DQ896147 ABM87146 U08137 AAC50071 U11821 AAC50124 X89102 CAA61474 NM_000639 NP_000630 NM_001302746 NP_001289675
Function	Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. {ECO:0000269|PubMed:17557115}.
Subcellular Location	FasL intracellular domain: Nucleus. Note=The FasL ICD cytoplasmic form is translocated into the nucleus.
Top Pathways	PI3K-Akt signaling pathway, Herpes simplex infection, Chagas disease (American trypanosomiasis), Non-alcoholic fatty liver disease (NAFLD), Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FAS-L CRISPR/Cas9 KO Plasmid (h) - sc-400562 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

FAS-L HDR Plasmid (h) - sc-400562-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

FAS-L Double Nickase Plasmid (h) - sc-400562-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

FAS-L Double Nickase Plasmid (h2) - sc-400562-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

FAS-L CRISPR Activation Plasmid (h) - sc-400562-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

FAS-L CRISPR Activation Plasmid (h2) - sc-400562-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

FAS-L Lentiviral Activation Particles (h) - sc-400562-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

FAS-L Lentiviral Activation Particles (h2) - sc-400562-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

FAS-L siRNA (h) - sc-29313 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

FAS-L shRNA Plasmid (h) - sc-29313-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

FAS-L shRNA (h) Lentiviral Particles - sc-29313-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

FAS-L siRNA (h2) - sc-270139 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

FAS-L shRNA Plasmid (h2) - sc-270139-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

FAS-L shRNA (h2) Lentiviral Particles - sc-270139-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU141661 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8488 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8488 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07001 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr07001

FASLG siRNA (Human) - CRH0252 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

Fas Ligand/TNFSF6 RNAi - H00000356-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

FASLG - MBS8220582 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human Fasl (NM_000639.1) - SHH292485 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human FASLG(NM_000639.1) - SHH049511 from Creative biogene Category siRNA Species Reactivities Human

FASLG shRNA Plasmid (Human) - CHH0252 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

FASLG miRNA 3'UTR clone - MiUTR3H-00783 from Creative biogene Species Reactivities Human

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