FASLG

Gene Symbol FASLG
Entrez Gene 356
Alt Symbol ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6
Species Human
Gene Type protein-coding
Description Fas ligand (TNF superfamily, member 6)
Other Description CD95 ligand|apoptosis (APO-1) antigen ligand 1|apoptosis antigen ligand|fas antigen ligand|tumor necrosis factor ligand superfamily member 6
Swissprots Q9BZP9 P48023
Accessions AAB96632 AAC39768 ABK41922 BAA32542 CAX86839 CBX53895 CCA94585 EAW90935 EAW90936 P48023 AF288573 AAG60017 AK314874 BAG37389 AY225406 AAO43991 AY858799 AAX49569 BC017502 AAH17502 D38122 BAA07320 DA916336 DQ893466 ABM84392 DQ896147 ABM87146 U08137 AAC50071 U11821 AAC50124 X89102 CAA61474 NM_000639 NP_000630 NM_001302746 NP_001289675
Function Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. {ECO:0000269|PubMed:17557115}.
Subcellular Location FasL intracellular domain: Nucleus. Note=The FasL ICD cytoplasmic form is translocated into the nucleus.
Top Pathways PI3K-Akt signaling pathway, Herpes simplex infection, Chagas disease (American trypanosomiasis), Non-alcoholic fatty liver disease (NAFLD), Proteoglycans in cancer

Active human Fas Ligand full length protein - ab157085 from Abcam

Category Protein
Prices $302.00
Sizes 10 µg
Source HEK 293 cells
Species Human
Activity Assay analysis: Inhibition of ab157085-mediated lysis. Fas (human):Fc (Human) (rec.) exerts its inhibitory activity in a concentration range of 0.5-5µg/ml in the presence of the enhancer (1µg/ml).

Active human Fas Ligand protein fragment - ab168908 from Abcam

Category Protein
Prices $588.00
Sizes 50 µg
Source HEK 293 cells
Species Human
SDS-PAGE analysis of ab168908 stained overnight with Coomassie Blue.

Active human Fas Ligand protein fragment - ab186673 from Abcam

Category Protein
Prices $110.00, $308.00
Sizes 2 µg, 10 µg
Source CHO
Species Human

Fas Ligand peptide - ab2441 from Abcam

Category Peptide

Human Fas Ligand full length protein - ab131850 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab131850 stained with Coomassie Blue.

Human Fas Ligand full length protein - ab139255 from Abcam

Category Protein
Source E. coli
Species Human
15% SDS-PAGE analysis of 3 µg ab139255.

Human Fas Ligand protein fragment - ab109359 from Abcam

Category Protein
Source HEK 293 cells
Species Human

FASLG / Fas Ligand Antibody Blocking Peptide - LS-E10662 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Fas Ligand/TNFSF6 Protein - NBP2-35264 from Novus Biologicals

Category Protein
Prices $69.00, $169.00, $3,469.00
Sizes 5 µg, 20 µg, 1 mg
Source E. coli
Species Human
SDS-Page: Human Fas Ligand/TNFSF6 Protein [NBP2-35264]

Fas Ligand/TNFSF6 Partial Recombinant Protein - H00000356-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Fas Ligand/TNFSF6 Recombinant Protein - H00000356-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Recombinant Human Fas Ligand/TNFSF6 Protein - NBP2-23039 from Novus Biologicals

Category Protein
Prices $269.00
Sizes 100 µg
Species Human
SDS-Page: Fas ligand Protein [NBP2-23039]

Fas Ligand/TNFSF6 Recombinant Protein - H00000356-G01 from Novus Biologicals

Category Protein
Prices $579.00
Sizes 10 µg
Species Human

Fas Ligand Recombinant Protein (Active) - GTX48225-PRO from GeneTex

Category Protein
Prices $299.00
Sizes 10 μg
Source Hamster
Species Human

Recombinant Human Fas Ligand/TNFSF6 - 126-FL-010 from R&D Systems

Category Protein
Source Chinese Hamster Ovary cell line, CHO-derived, Pro134-Leu281, with an N-terminal Met and 6-His tag

Recombinant Human Fas Ligand/TNFSF6, CF - 126-FL-010/CF from R&D Systems

Category Protein
Source Chinese Hamster Ovary cell line, CHO-derived, Pro134-Leu281, with an N-terminal Met and 6-His tag

Recombinant Mouse Fas Ligand/TNFSF6 - 526-SA-050 from R&D Systems

Category Protein
Source Mouse myeloma cell line, NS0-derived, Pro132-Leu279, with an N-terminal Met and 6-His tag

Recombinant Mouse Fas Ligand/TNFSF6, CF - 526-SA-050/CF from R&D Systems

Category Protein
Source Mouse myeloma cell line, NS0-derived, Pro132-Leu279, with an N-terminal Met and 6-His tag

Human FASLG protein - orb244199 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

Human FASLG protein - orb244198 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

Human CD95L protein (His Tag) - orb138500 from Biorbyt

Category Protein
Prices $434.00, $646.00
Sizes 10 μg, 20 μg
Source Yeast
Species Human
SDS-PAGE analysis of human CD95L protein (His Tag)

Human FASLG protein - orb245832 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

FasL protein - 30R-AF033 from Fitzgerald

Category Protein
Prices $225.00
Sizes 10 µg
Source CHO cells

FASLG Blocking Peptide - 33R-6103 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

FASLG protein (His tag) - 30R-2954 from Fitzgerald

Category Protein
Prices $270.00
Sizes 100 µg
Source E.coli
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