RAB35

Gene Symbol	RAB35
Entrez Gene	11021
Alt Symbol	H-ray, RAB1C, RAY
Species	Human
Gene Type	protein-coding
Description	RAB35, member RAS oncogene family
Other Description	GTP-binding protein RAY|ras-related protein Rab-35|ras-related protein rab-1c (GTP-binding protein ray)
Swissprots	B2R6E0 Q15286 B4E390
Accessions	AAC83182 CAJ34551 CCD32725 EAW98163 EAW98164 Q15286 AF498960 AAM21108 AI042456 AK001309 AK125543 AK298391 BAG60626 AK300127 BAG61918 AK304620 BAG65402 AK312538 BAG35437 BC015931 AAH15931 BC017753 BM467132 BP303346 BQ233709 BT020024 AAV38827 CR536486 CAG38725 CR541683 CAG46484 DC349830 DC370610 DC408044 DQ890586 ABM92203 DQ890603 ABM92220 DQ893750 ABM84676 X79781 CAA56177 XM_011537779 XP_011536081 NM_001167606 NP_001161078 NM_006861 NP_006852
Function	The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in the process of endocytosis and is an essential rate-limiting regulator of the fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localization at the intercellular bridge. May indirectly regulate neurite outgrowth. {ECO:0000269|PubMed:16950109, ECO:0000269|PubMed:21951725}.
Subcellular Location	Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Membrane, clathrin- coated pit. Cytoplasmic vesicle, clathrin-coated vesicle. Endosome. Melanosome. Note=Present on sorting endosomes and recycling endosome tubules. Tends to be enriched in PIP2-positive cell membrane domains. During mitosis, associated with the plasma membrane and present at the ingressing furrow during early cytokinesis as well as at the intercellular bridge later during cytokinesis. Identified in stage I to stage IV melanosomes.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rab35 Antibody - 9690 from Cell Signaling Technology Prices $246.00 Sizes 100 µl (10 western blots) Host Rabbit Clonality Polyclonal

pan Rab (W-18) - sc-109473 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-RAB35 antibody - ab137958 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RAB35 antibody [1A5B7] - ab170145 from Abcam Host Mouse Clonality Monoclonal Clone 1A5B7

Anti-RAB35 antibody - C-terminal - ab173964 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-RAB35 Antibody (C-Terminus) - LS-C348302 from LifeSpan Bioscience Prices $375.00 Sizes 200 µl Host Goat Clonality Polyclonal

Anti-RAB35 Antibody (aa166-199) - LS-C344271 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-RAB35 Antibody (C-Terminus) - LS-C190141 from LifeSpan Bioscience Prices $515.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RAB35 Antibody (aa171-199, AP) - LS-C267696 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RAB35 Antibody (aa171-199, APC) - LS-C267697 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RAB35 Antibody (aa171-199, Biotin) - LS-C267698 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RAB35 Antibody (aa71-120) - LS-C116469 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-RAB35 Antibody (aa87-136) - LS-C200552 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RAB35 Antibody (aa171-199, FITC) - LS-C267699 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RAB35 Antibody (C-Terminus) - LS-C116470 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-RAB35 Antibody (aa171-199, Azide-free, HRP) - LS-C267700 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RAB35 Antibody (aa171-199, PE) - LS-C267702 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RAB35 Antibody (aa99-148) - LS-C291372 from LifeSpan Bioscience Prices $315.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RAB35 Antibody (aa146-191) - LS-C313903 from LifeSpan Bioscience Prices $345.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RAB35 Antibody (aa170-200) - LS-C324478 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-RAB35 Antibody (aa171-199) - LS-C158788 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

RAB35 Antibody - NBP2-20042 from Novus Biologicals Prices $349.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RAB35 Antibody - NBP1-79484 from Novus Biologicals Prices $139.00, $329.00 Sizes 20 µl, 100 µl Host Rabbit Clonality Polyclonal

RAB35 Antibody - NBP1-79483 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

IRE1a (Ser726) Polyclonal Antibody - bs-4308R from Bioss Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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