RAB35

Gene Symbol	RAB35
Entrez Gene	11021
Alt Symbol	H-ray, RAB1C, RAY
Species	Human
Gene Type	protein-coding
Description	RAB35, member RAS oncogene family
Other Description	GTP-binding protein RAY|ras-related protein Rab-35|ras-related protein rab-1c (GTP-binding protein ray)
Swissprots	B2R6E0 Q15286 B4E390
Accessions	AAC83182 CAJ34551 CCD32725 EAW98163 EAW98164 Q15286 AF498960 AAM21108 AI042456 AK001309 AK125543 AK298391 BAG60626 AK300127 BAG61918 AK304620 BAG65402 AK312538 BAG35437 BC015931 AAH15931 BC017753 BM467132 BP303346 BQ233709 BT020024 AAV38827 CR536486 CAG38725 CR541683 CAG46484 DC349830 DC370610 DC408044 DQ890586 ABM92203 DQ890603 ABM92220 DQ893750 ABM84676 X79781 CAA56177 XM_011537779 XP_011536081 NM_001167606 NP_001161078 NM_006861 NP_006852
Function	The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in the process of endocytosis and is an essential rate-limiting regulator of the fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localization at the intercellular bridge. May indirectly regulate neurite outgrowth. {ECO:0000269|PubMed:16950109, ECO:0000269|PubMed:21951725}.
Subcellular Location	Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Membrane, clathrin- coated pit. Cytoplasmic vesicle, clathrin-coated vesicle. Endosome. Melanosome. Note=Present on sorting endosomes and recycling endosome tubules. Tends to be enriched in PIP2-positive cell membrane domains. During mitosis, associated with the plasma membrane and present at the ingressing furrow during early cytokinesis as well as at the intercellular bridge later during cytokinesis. Identified in stage I to stage IV melanosomes.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RAB35 (mutated Q67 L) full length protein - ab176632 from Abcam Category Protein Source E. coli Species Human

Human RAB35 full length protein - ab113586 from Abcam Category Protein Source E. coli Species Human

RAB35 Antibody Blocking Peptide - LS-E5636 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAB35 Antibody Blocking Peptide - LS-E18782 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAB35 Antibody Blocking Peptide - LS-E18781 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAB35 Recombinant Protein - H00011021-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human RAB35 Protein - NBP1-72460 from Novus Biologicals Category Protein Prices $349.00, $969.00 Sizes 50 µg, 250 µg Source E. coli Species Human

RAB35-Antibody-C-term-Blocking-Peptide - BP18164b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human RAB35 protein - orb169146 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

RAB35 Blocking Peptide - 33R-8227 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RAB35 Blocking Peptide - 33R-3341 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RAB35 protein (His tag) - 80R-1974 from Fitzgerald Category Protein Prices $365.00 Sizes 50 µg Source E.coli

RAB35 Blocking Peptide - abx063720 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine

RAB35 / RAB1C (1-203, His-tag) - AR50043PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 250 µg Source E. coli Species Human

RAB35 / RAB1C (1-203, His-tag) - AR50043PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 50 µg Source E. coli Species Human

RAB35 / RAB1C - H00011021-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

RAB35 / RAB1C - H00011021-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

RAB35, Member RAS Oncogene Family, Human Recombinant - 228-13374-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human RAB35, Member RAS Oncogene Family - 228-13374-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human RAB35, Member RAS Oncogene Family - 228-13374-3 from RayBiotech Category Protein Source Escherichia Coli. Species Human

RAB35, 1-203 aa, Human, His tag, E.coli - 01-RAB35 from ARP American Research Products Category Protein Prices $179.00, $449.00, $1,089.00 Sizes 10 µg, 50 µg, 250 µg Species Human

RAB35 fusion protein - Ag1872 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

RAB35 Human - PRPS-942 from NeoScientific Category Protein Prices $65.00, $169.00, $6,760.00 Sizes 2 µg, 10 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human RAB35, Member RAS Oncogene Family Protein - BP002345-PRO-935 from Syd Labs Category Protein Prices $160.00, $5,200.00 Sizes 10 µg, 1 mg Source E. coli-derived. Species Human

RAB35, 1-203 aa, Recombinant Protein - GWB-P0820A from Genway Biotech Category Protein Prices $400.00, $1,200.00 Sizes 50 μg, 250 μg Source E.coli Species Human

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