APOE

Gene Symbol	APOE
Entrez Gene	348
Alt Symbol	AD2, APO-E, LDLCQ5, LPG
Species	Human
Gene Type	protein-coding
Description	apolipoprotein E
Other Description	apolipoprotein E3
Swissprots	Q9P2S4 P02649 C0JYY5 B2RC15
Accessions	AAB59397 AAD02505 AAG27089 AAL82810 ACN81314 ADK26133 AFS60672 BAA96080 CAA63051 EAW57306 P02649 AK308546 AK314898 BAG37412 AL037046 BC003557 AAH03557 BI550631 BM042032 BU848796 CA771535 DB486513 DQ892548 ABM83474 DQ895759 ABM86685 HY056112 HY074384 HY074888 K00396 AAB59546 M12529 AAB59518 X00199 CAA25017 Z70760 CAA94806 NM_000041 NP_000032 NM_001302688 NP_001289617 NM_001302689 NP_001289618 NM_001302690 NP_001289619 NM_001302691 NP_001289620
Function	Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
Subcellular Location	Secreted.
Tissue Specificity	Occurs in all lipoprotein fractions in plasma. It constitutes 10-20% of very low density lipoproteins (VLDL) and 1-2% of high density lipoproteins (HDL). APOE is produced in most organs. Significant quantities are produced in liver, brain, spleen, lung, adrenal, ovary, kidney and muscle.
Top Pathways	Alzheimer's disease

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Apolipoprotein E (APOE) Human ELISA Kit - ab108813 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity = 0.03 µg/ml Range 0.031 µg/ml - 2 µg/ml

Mouse APOE / Apolipoprotein E ELISA Kit (Sandwich ELISA) - LS-F4714 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 15.63 ng/ml Range 15.63-1000 ng/ml

Rat APOE / Apolipoprotein E ELISA Kit (Sandwich ELISA) - LS-F4713 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 2.55 ng/ml Range 15.63-1000 ng/ml

Rabbit APOE / Apolipoprotein E ELISA Kit (Competitive EIA) - LS-F4735 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 182.5 pg/ml Range 15.63-1000 ng/ml

Human APOE / Apolipoprotein E ELISA Kit (Sandwich ELISA) - LS-F4712 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 1.8 ng/ml Range 15.63-1000 ng/ml

Pig APOE / Apolipoprotein E ELISA Kit (Sandwich ELISA) - LS-F6306 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.144 ng/ml Range 15.63-1000 ng/ml

Dog APOE / Apolipoprotein E ELISA Kit (Sandwich ELISA) - LS-F9737 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.65 ng/ml Range 15.63-1000 ng/ml

Rat APOE / Apolipoprotein E ELISA Kit (Competitive EIA) - LS-F10098 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 15.6 ng/ml Range 15.63-1000 ng/ml

Human APOE / Apolipoprotein E ELISA Kit (Competitive EIA) - LS-F10097 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 3.9 ng/ml Range 15.63-1000 ng/ml

Mouse APOE / Apolipoprotein E ELISA Kit (Competitive EIA) - LS-F10099 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 1.56 ng/ml Range 15.63-1000 ng/ml

Rabbit APOE / Apolipoprotein E ELISA Kit (Competitive EIA) - LS-F10102 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 3.9 ng/ml Range 15.63-1000 ng/ml

Pig APOE / Apolipoprotein E ELISA Kit (Competitive EIA) - LS-F10327 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 7.81 ng/ml Range 15.63-1000 ng/ml

Dog APOE / Apolipoprotein E ELISA Kit (Sandwich ELISA) - LS-F10342 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 7.81 ng/ml Range 15.63-1000 ng/ml

Goat APOE / Apolipoprotein E ELISA Kit (Competitive EIA) - LS-F10341 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 7.81 ng/ml Range 15.63-1000 ng/ml

Guinea pig APOE / Apolipoprotein E ELISA Kit (Competitive EIA) - LS-F10344 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 6.25 ng/ml Range 15.63-1000 ng/ml

Bovine APOE / Apolipoprotein E ELISA Kit (Competitive EIA) - LS-F10343 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 7.81 ng/ml Range 15.63-1000 ng/ml

Horse APOE / Apolipoprotein E ELISA Kit (Competitive EIA) - LS-F10345 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 9.4 ng/ml Range 15.63-1000 ng/ml

Sheep APOE / Apolipoprotein E ELISA Kit (Competitive EIA) - LS-F10346 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 31.25 ng/nl Range 15.63-1000 ng/ml

Duck APOE / Apolipoprotein E ELISA Kit (Competitive EIA) - LS-F10190 from LifeSpan Bioscience Category ELISA Kit Prices $630.00 Sizes 1 plate Sensitivity 0.113 µg/ml Range 15.63-1000 ng/ml

Hamster APOE / Apolipoprotein E ELISA Kit (Competitive EIA) - LS-F10191 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 7 ng/ml Range 15.63-1000 ng/ml

Rat APOE / Apolipoprotein E ELISA Kit (Sandwich ELISA) - LS-F10874 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 7.8 Range 15.63-1000 ng/ml

Rabbit APOE / Apolipoprotein E ELISA Kit - LS-F10873 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 7.8 Range 7.8 - 500 ng/ml

Human APOE / Apolipoprotein E ELISA Kit (Sandwich ELISA) - LS-F10872 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 7.8 Range 15.63-1000 ng/ml

Human APOE / Apolipoprotein E 3 ELISA Kit - RAB0615 from Sigma-Aldrich Category ELISA Kit Prices $637.00 Sizes 1 kt

Human APOE / Apolipoprotein E 4 ELISA Kit - RAB0616 from Sigma-Aldrich Category ELISA Kit Prices $637.00 Sizes 1 kt

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