APOE

Gene Symbol	APOE
Entrez Gene	348
Alt Symbol	AD2, APO-E, LDLCQ5, LPG
Species	Human
Gene Type	protein-coding
Description	apolipoprotein E
Other Description	apolipoprotein E3
Swissprots	Q9P2S4 P02649 C0JYY5 B2RC15
Accessions	AAB59397 AAD02505 AAG27089 AAL82810 ACN81314 ADK26133 AFS60672 BAA96080 CAA63051 EAW57306 P02649 AK308546 AK314898 BAG37412 AL037046 BC003557 AAH03557 BI550631 BM042032 BU848796 CA771535 DB486513 DQ892548 ABM83474 DQ895759 ABM86685 HY056112 HY074384 HY074888 K00396 AAB59546 M12529 AAB59518 X00199 CAA25017 Z70760 CAA94806 NM_000041 NP_000032 NM_001302688 NP_001289617 NM_001302689 NP_001289618 NM_001302690 NP_001289619 NM_001302691 NP_001289620
Function	Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
Subcellular Location	Secreted.
Tissue Specificity	Occurs in all lipoprotein fractions in plasma. It constitutes 10-20% of very low density lipoproteins (VLDL) and 1-2% of high density lipoproteins (HDL). APOE is produced in most organs. Significant quantities are produced in liver, brain, spleen, lung, adrenal, ovary, kidney and muscle.
Top Pathways	Alzheimer's disease

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

APOE - MBS1272728 from MyBioSource Species Human Accession BC003557

Human APOE cDNA clone(NM_000041.2) - CDFH000989 from Creative Biomart Species Human Accession NM_000041.2

Human ApoE ORF clone(NM_000041.2) - CDCL182727 from Creative Biomart Species Human Accession NM_000041.2

Human APOE ORF Clone(NM_000041.2) - CDCR277750 from Creative Biomart Species Human Accession NM_000041.2

Human APOE ORF Clone(NM_000041.2) - CDCR277751 from Creative Biomart Species Human Accession NM_000041.2

Human APOE ORF Clone(NM_000041.2) - CDCR277752 from Creative Biomart Species Human Accession NM_000041.2

Human APOE ORF Clone(NM_000041.2) - CDCL154143 from Creative Biomart Species Human Accession NM_000041.2

Human ApoE Gene cDNA clone plasmid - HG10817-M from Sino Biological Species Human

Human ApoE/Apolipoprotein E Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10817-ACR from Sino Biological Species Human

Human ApoE Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-tagged - HG10817-M-F from Sino Biological Species Human Accession NM_000041.2

Human ApoE/Apolipoprotein E Gene ORF cDNA clone expression plasmid, C-His tag - HG10817-M-H from Sino Biological Species Human

Human ApoE/Apolipoprotein E Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10817-ACG from Sino Biological Species Human

Human ApoE/Apolipoprotein E Gene ORF cDNA clone expression plasmid - HG10817-UT from Sino Biological Species Human

Human ApoE/Apolipoprotein E Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10817-NF from Sino Biological Species Human

Human ApoE/Apolipoprotein E Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10817-NM from Sino Biological Species Human

Human ApoE/Apolipoprotein E Gene ORF cDNA clone expression plasmid, C-HA tag - HG10817-CY from Sino Biological Species Human

Human ApoE/Apolipoprotein E Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10817-CF from Sino Biological Species Human

Human ApoE/Apolipoprotein E Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10817-CM from Sino Biological Species Human

Human ApoE/Apolipoprotein E Gene ORF cDNA clone expression plasmid, N-His tag - HG10817-NH from Sino Biological Species Human

Human ApoE/Apolipoprotein E Gene ORF cDNA clone expression plasmid, N-HA tag - HG10817-NY from Sino Biological Species Human

Human ApoE/Apolipoprotein E Gene ORF cDNA clone expression plasmid, C-His tag - HG10817-CH from Sino Biological Species Human

ApoE - CL01158H01 from Elabscience Species Human Accession NM_000041.2

Human ApoE ORF clone(NM_000041.2) - CDCL182727 from Creative biogene Species Human

Human APOE ORF Clone (BC003557) - CDCS405372 from Creative biogene Species Human Accession P02649

Human APOE cDNA Clone(NM_000041.2) - CDFH000989 from Creative biogene Species Human

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