PLCG1

Gene Symbol	PLCG1
Entrez Gene	5335
Alt Symbol	NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1
Species	Human
Gene Type	protein-coding
Description	phospholipase C, gamma 1
Other Description	1-phosphatidyl-D-myo-inositol-4,5-bisphosphate|1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1|PLC-148|PLC-gamma-1|inositoltrisphosphohydrolase|monophosphatidylinositol phosphodiesterase|phosphatidylinositol phospholipase C|phosphoinositidase C|phosphoinositide phospholipase C|phosphoinositide phospholipase C-gamma-1|phospholipase C, gamma 1 (formerly subtype 148)|phospholipase C-148|phospholipase C-II|phospholipase C-gamma-1|triphosphoinositide phosphodiesterase
Swissprots	E1P5W4 Q2V575 B9EGH4 B7ZLY7 P19174
Accessions	AAB70663 ABB84466 EAW75989 EAW75990 EAW75991 EAW75992 EAW75993 P19174 AB210028 BAE06110 AF147391 AK297370 BAG59815 AK309606 AL110247 CAB53696 BC136466 AAI36467 BC144136 AAI44137 BX415739 BX434193 M34667 AAA36452 XM_005260438 XP_005260495 XM_011528865 XP_011527167 XM_011528866 XP_011527168 XM_011528867 XP_011527169 XR_936550 NM_002660 NP_002651 NM_182811 NP_877963
Function	Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand- mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration. {ECO:0000269|PubMed:17229814}.
Subcellular Location	Cell projection, lamellipodium. Cell projection, ruffle. Note=Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment.
Top Pathways	Epstein-Barr virus infection, MicroRNAs in cancer, Inflammatory mediator regulation of TRP channels, Choline metabolism in cancer, Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PLCG1 ELISA Kit (Sandwich ELISA) - LS-F4829 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 0.057 ng/ml Range 0.156-10 ng/ml

Mouse/Human/Rat Phospho-PLCG1 (Tyr771) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1093 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.156-10 ng/ml

Mouse/Human/Rat Phospho-PLCG1 (Tyr783) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1094 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.156-10 ng/ml

Mouse/Human/Rat Phospho-PLCG1 (Tyr1253) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1209 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.156-10 ng/ml

Mouse/Human/Rat PLCG1 ELISA Kit (Cell-Based ELISA) - LS-F2258 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.156-10 ng/ml

Human PLCG1 ELISA Kit (Sandwich ELISA) - LS-F12344 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

Human PLCg1 ELISA Kit - abx152774 from Abbexa Category ELISA Kit Sensitivity 0.068 ng/ml Range 0.156 ng/ml - 10 ng/ml

1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma-1 (PLCG1), Human, ELISA Kit - E01P0910 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 1.0-25ng/ml

1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1, PLCG1, Human, ELISA Kit - E0269h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

Phospholipase C Gamma 1 (PLCg1), Human, ELISA Kit - SEA269Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 0.068ng/mL Range 0.156-10ng/mL

Phospholipase C Gamma 1, PLCy1, Human, ELISA Kit - E-EL-H1718 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Phospholipase C Gamma 1, PLCg1, Mouse, ELISA Kit - E-EL-M0904 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Phospholipase C Gamma 1, PLCg1, Rat, ELISA Kit - E-EL-R0735 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Phospholipase C Gamma 1, PLCy1, Rabbit, ELISA Kit - E-EL-RB1850 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Phospholipase C Gamma 1, PLCy1, Chicken, ELISA Kit - E-EL-Ch0275 from ARP American Research Products Category ELISA Kit Prices $445.50 Sizes 96 t

Phospholipase C Gamma 1, PLCy1, Porcine, ELISA Kit - E-EL-P1900 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Phospholipase C Gamma 1, PLCy1, Sheep, ELISA Kit - E-EL-S0386 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Phospholipase C Gamma 1, PLCy1, Monkey, ELISA Kit - E-EL-MK1877 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human PLCg1 ELISA Kit - HP0133 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine PLCg1 ELISA Kit - AP0133 from NeoScientific Category ELISA Kit Prices $300.00, $480.00 Sizes 100 µl, 200 µl

PLCG1 Colorimetric Cell-Based ELISA Kit - CB5574 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

PLCG1 (Phospho-Tyr771) Colorimetric Cell-Based ELISA Kit - CBP1072 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

PLCG1 (Phospho-Tyr783) Colorimetric Cell-Based ELISA Kit - CBP1073 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

PLCG1 (Phospho-Tyr1253) Colorimetric Cell-Based ELISA Kit - CBP1202 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

ELISA Kit for Phospholipase C Gamma 1 (PLCg1) - SEA269Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.057ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

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