CA2

Gene Symbol CA2
Entrez Gene 760
Alt Symbol CA-II, CAC, CAII, Car2, HEL-76
Species Human
Gene Type protein-coding
Description carbonic anhydrase II
Other Description carbonate dehydratase II|carbonic anhydrase 2|carbonic anhydrase B|carbonic anhydrase C|carbonic dehydratase|epididymis luminal protein 76
Swissprots Q96ET9 P00918 Q6FI12 B2R7G8
Accessions AAA51909 CAA27012 EAW87136 P00918 AF015039 AK123309 AK312978 BAG35815 BC011949 AAH11949 BC035424 CD013933 CR536526 CAG38763 CR541875 CAG46673 DA431650 DQ891320 ABM82246 DQ894504 ABM85430 FJ224289 ACI45981 J03037 AAA51908 M36532 AAA51911 S69526 AAB30170 Y00339 CAA68426 NM_000067 NP_000058 NM_001293675 NP_001280604
Function Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6. {ECO:0000250, ECO:0000269|PubMed:10550681, ECO:0000269|PubMed:11831900, ECO:0000269|PubMed:15990874}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15990874}. Cell membrane {ECO:0000269|PubMed:15990874}. Note=Colocalized with SLC26A6 at the surface of the cell membrane in order to form a bicarbonate transport metabolon. Displaced from the cytosolic surface of the cell membrane by PKC in phorbol myristate acetate (PMA)-induced cells.
Top Pathways Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion

CA2 293 Cell Lysate - 410334 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

Carbonic Anhydrase II/CA2 Overexpression Lysate (Native) - NBL1-08615 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Carbonic Anhydrase II Overexpression Lysate (Adult Normal) [NBL1-08615] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Carbonic Anhydrase II.

CA II (h): 293T Lysate - sc-113038 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

CA II (h4): 293T Lysate - sc-158314 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

CA2 Over-expression Lysate Product - GWB-578B82 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human CA2 Knockdown Stable Cell Line - CSC-DC002230 from Creative biogene

Category Cell Line
Species Human

Human CA2 Knockout Cell Line-HeLa - CSC-RT1667 from Creative biogene

Category Cell Line
Species Human

CA2 KO Cell Lysate-HeLa - CLKO-1514 from Creative biogene

Category Cell Lysate
Search more