CA2

Gene Symbol CA2
Entrez Gene 760
Alt Symbol CA-II, CAC, CAII, Car2, HEL-76
Species Human
Gene Type protein-coding
Description carbonic anhydrase II
Other Description carbonate dehydratase II|carbonic anhydrase 2|carbonic anhydrase B|carbonic anhydrase C|carbonic dehydratase|epididymis luminal protein 76
Swissprots Q96ET9 P00918 Q6FI12 B2R7G8
Accessions AAA51909 CAA27012 EAW87136 P00918 AF015039 AK123309 AK312978 BAG35815 BC011949 AAH11949 BC035424 CD013933 CR536526 CAG38763 CR541875 CAG46673 DA431650 DQ891320 ABM82246 DQ894504 ABM85430 FJ224289 ACI45981 J03037 AAA51908 M36532 AAA51911 S69526 AAB30170 Y00339 CAA68426 NM_000067 NP_000058 NM_001293675 NP_001280604
Function Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6. {ECO:0000250, ECO:0000269|PubMed:10550681, ECO:0000269|PubMed:11831900, ECO:0000269|PubMed:15990874}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15990874}. Cell membrane {ECO:0000269|PubMed:15990874}. Note=Colocalized with SLC26A6 at the surface of the cell membrane in order to form a bicarbonate transport metabolon. Displaced from the cytosolic surface of the cell membrane by PKC in phorbol myristate acetate (PMA)-induced cells.
Top Pathways Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion

Active human Carbonic Anhydrase II full length protein - ab167716 from Abcam

Category Protein
Prices $352.00
Sizes 100 µg
Source HEK 293 cells
Species Human
SDS-PAGE of reduced ab167716 stained overnight with Coomassie Blue.

E. coli Carbonic Anhydrase II full length protein - ab87351 from Abcam

Category Protein
Prices $228.00, $921.00
Sizes 100 µg, 500 µg
Source E. coli
Species Escherichia coli
ab87351 on 15% SDS-PAGE (3&microg)

Human Carbonic Anhydrase II full length protein - ab85484 from Abcam

Category Protein
Prices $188.00
Sizes 50 µg
Source E. coli
Species Human
15% SDS-PAGE analysis of 3µg ab85484

Human Carbonic Anhydrase II full length protein - ab186978 from Abcam

Category Protein
Prices $319.00
Sizes 100 µg
Source E. coli
Species Human

Human Carbonic Anhydrase II peptide - ab92423 from Abcam

Category Peptide
Prices $176.00
Sizes 100 µg

CA2 / Carbonic Anhydrase II Antibody Blocking Peptide - LS-E8847 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CA2 / Carbonic Anhydrase II Antibody Blocking Peptide - LS-E22002 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CA2 / Carbonic Anhydrase II Antibody Blocking Peptide - LS-E22001 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Carbonic Anhydrase II/CA2 Protein - H00000760-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human Carbonic Anhydrase II/CA2 Protein - NBC1-28002 from Novus Biologicals

Category Protein
Prices $349.00
Sizes 100 µg
Species Human
SDS-Page: Carbonic Anhydrase II/CA2 Protein [NBC1-28002]

Carbonic Anhydrase II/CA2 Recombinant Protein - P3488 from Novus Biologicals

Category Protein
Prices $669.00
Sizes 100 µg
Species Human

CA2-Antibody-N-term-Blocking-Peptide - BP7307a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Human Carbonic Anhydrase II, CF - 2184-CA-050 from R&D Systems

Category Protein
Source E. coli-derived, Ser2-Lys260, with C-terminal 10-His tag

Carbonic Anhydrase 2 Protein (OPPA02141) - OPPA02141 from Aviva Systems Biology

Category Protein
Prices $100.00
Sizes 5 µg
Source E. Coli

Human CA2 protein - orb244062 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

E.coli Carbonic Anhydrase 2 protein - orb90048 from Biorbyt

Category Protein
Prices $170.00, $289.00
Sizes 5 μg, 25 μg
Source E.coli

Human Carbonic Anhydrase 2 protein - orb90049 from Biorbyt

Category Protein
Prices $230.00, $442.00
Sizes 5 μg, 20 μg
Source E.coli
Species Human

Human CA2 His tag protein - orb83996 from Biorbyt

Category Protein
Prices $417.00, $570.00
Sizes 50 μg, 100 μg
Source E. coli
Species Human
SDS-PAGE analysis of human CA2 His tag protein

CA2 Blocking Peptide - 33R-8709 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

CA2 Blocking Peptide - 33R-2905 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

Carbonic anhydrase II protein - 30R-1325 from Fitzgerald

Category Protein
Prices $340.00
Sizes 100 µg
Source E.coli

Carbonic Anhydrase 2 Blocking Peptide - abx062314 from Abbexa

Category Peptide
Species Human, Rat, Monkey

Human Carbonic Anhydrase II Protein - abx065684 from Abbexa

Category Protein
Source E.coli
Species Human

Human Carbonic Anhydrase II Protein - abx065685 from Abbexa

Category Protein
Source E.coli
Species Human

Human Carbonic Anhydrase II Protein - abx065686 from Abbexa

Category Protein
Source E.coli
Species Human
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