Gene Symbol | NOS3 |
---|---|
Entrez Gene | 287024 |
Alt Symbol | - |
Species | Bovine |
Gene Type | protein-coding |
Description | nitric oxide synthase 3 (endothelial cell) |
Other Description | EC-NOS|NOS type III|NOSIII|cNOS|constitutive NOS|eNOS|endothelial NOS|endothelial nitric oxide synthase|nitric oxide synthase, endothelial |
Swissprots | P29473 |
Accessions | CAA02941 DAA30266 P29473 M89952 AAA30494 M95674 AAA30669 M99057 AAA30667 NM_181037 NP_851380 |
Function | Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:17071725}. Membrane, caveola {ECO:0000269|PubMed:17071725}. Cytoplasm, cytoskeleton {ECO:0000250}. Golgi apparatus {ECO:0000269|PubMed:17071725}. Note=Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity. {ECO:0000250}. |
Top Pathways | Sphingolipid signaling pathway, cGMP-PKG signaling pathway, Oxytocin signaling pathway, Estrogen signaling pathway, PI3K-Akt signaling pathway |
Endothelial Nitric Oxide Synthase, Bovine, ELISA Kit - E11N0024 from ARP American Research Products
|
||||||||||
Nitric oxide synthase, endothelial, NOS3, Bovine, ELISA Kit - E0815b from ARP American Research Products
|
||||||||||
Bovine eNOS ELISA Kit - BN0031 from NeoScientific
|
||||||||||
Endothelial Nitric Oxide Synthase, ELISA Kit - MBS038506 from MyBioSource
|
||||||||||
Endothelial Nitric Oxide Synthase, ELISA Kit - MBS740781 from MyBioSource
|
||||||||||
nitric oxide synthase 3 (endothelial cell) , ELISA Kit - MBS9310116 from MyBioSource
|
||||||||||
Bovine Endothelial Nitric Oxide Synthase ELISA - E11N0024 from BlueGene Biotech
|
||||||||||
Bovine NOS3 ELISA Kit - E091484 from Biobool
|
||||||||||
Bovine eNOS ELISA Kit - EBN0031 from ABclonal
|
||||||||||
Nitric oxide synthase, ELISA Kit - MBS2881526 from MyBioSource
|
||||||||||
Nitric oxide synthase, endothelial, ELISA Kit - MBS765164 from MyBioSource
|
||||||||||
NOS3/eNOS (Nitric oxide synthase, endothelial), ELISA Kit - MBS7606686 from MyBioSource
|