Neu1

Gene Symbol Neu1
Entrez Gene 18010
Alt Symbol AA407268, AA407316, Aglp, Apl, Bat-7, Bat7, G9, Map-2, Neu, Neu-1
Species Mouse
Gene Type protein-coding
Description neuraminidase 1
Other Description G9 sialidase|HLA-B-associated transcript 7|N-acetyl-alpha-neuraminidase 1|lysosomal sialidase|sialidase 1|sialidase-1
Swissprots O55220 Q99KG9 O35657
Accessions AAC84167 CAD91185 EDL26719 EDL26720 EDL26721 O35657 AK077444 AK138332 AK145680 BAE26586 AK148229 AK182863 AK186151 AK186636 AK187229 AK187684 AK189610 AK190751 AK193377 AK200662 AK200961 AK210577 AK212019 BC004666 AAH04666 BY281600 U93702 AAC53536 Y11412 CAA72215 NM_010893 NP_035023
Function Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moities from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage. {ECO:0000269|PubMed:9363440, ECO:0000269|PubMed:9384611}.
Subcellular Location Lysosome membrane {ECO:0000269|PubMed:9384611}; Peripheral membrane protein {ECO:0000269|PubMed:9384611}; Lumenal side {ECO:0000269|PubMed:9384611}. Lysosome lumen {ECO:0000269|PubMed:9384611}. Cell membrane {ECO:0000269|PubMed:9384611}. Cytoplasmic vesicle {ECO:0000269|PubMed:9384611}. Note=Localized not only on the inner side of the lysosomal membrane and in the lysosomal lumen, but also on the plasma membrane and in intracellular vesicles.
Tissue Specificity Highly expressed in kidney, epididymis, followed by brain, spinal cord and weakly expressed in adrenal, heart, liver, lung and spleen. {ECO:0000269|PubMed:9384611}.
Top Pathways Lysosome, Sphingolipid metabolism, Other glycan degradation

Neu1 CRISPR/Cas9 KO Plasmid (m) - sc-421856 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Neu1 HDR Plasmid (m) - sc-421856-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Neu1 Double Nickase Plasmid (m) - sc-421856-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Neu1 Double Nickase Plasmid (m2) - sc-421856-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Neu1 CRISPR Activation Plasmid (m) - sc-421856-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Neu1 CRISPR Activation Plasmid (m2) - sc-421856-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Neu1 Lentiviral Activation Particles (m) - sc-421856-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Neu1 Lentiviral Activation Particles (m2) - sc-421856-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Neu1 siRNA (m) - sc-149919 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Neu1 shRNA Plasmid (m) - sc-149919-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Neu1 shRNA (m) Lentiviral Particles - sc-149919-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU032751 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN36369 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND36369 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

NEU1 siRNA (Mouse) - CRM2738 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse NEU1 (NM_010893.3) - SHH351448 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse NEU1 siRNA - orb282214 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

NEU1 shRNA Plasmid (Mouse) - CHM2738 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse
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