| Gene Symbol |
Nr1i3
|
| Entrez Gene |
12355
|
| Alt Symbol |
AA209988, AI551208, CAR, CAR-beta, Care2, ESTM32, MB67
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
nuclear receptor subfamily 1, group I, member 3
|
| Other Description |
constitutive androstane receptor|constitutively transactivates RAREs|nuclear receptor subfamily 1 group I member 3|orphan nuclear receptor MB67
|
| Swissprots |
O35627 Q3V008 O35628
|
| Accessions |
EDL39125 EDL39126 EDL39127 O35627 AF009327 AAC53349 AF009328 AAC53350 AI132241 AK133515 BAE21697 AK149381 AK149430 BAE28870 BC025154 BC037645 AAH37645 BC089541 AAH89541 XM_006496628 XP_006496691 XM_006496629 XP_006496692 XM_006496630 XP_006496693 XM_006496631 XP_006496694 XM_006496632 XP_006496695 XM_011238743 XP_011237045 XM_011238744 XP_011237046 XR_373594 XR_373595 NM_001243062 NP_001229991 NM_001243063 NP_001229992 NM_009803 NP_033933
|
| Function |
Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Recruited to the cytoplasm by DNAJC7.
|
| Tissue Specificity |
Predominantly expressed in liver.
|