Gene Symbol | Nr1i3 |
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Entrez Gene | 12355 |
Alt Symbol | AA209988, AI551208, CAR, CAR-beta, Care2, ESTM32, MB67 |
Species | Mouse |
Gene Type | protein-coding |
Description | nuclear receptor subfamily 1, group I, member 3 |
Other Description | constitutive androstane receptor|constitutively transactivates RAREs|nuclear receptor subfamily 1 group I member 3|orphan nuclear receptor MB67 |
Swissprots | O35627 Q3V008 O35628 |
Accessions | EDL39125 EDL39126 EDL39127 O35627 AF009327 AAC53349 AF009328 AAC53350 AI132241 AK133515 BAE21697 AK149381 AK149430 BAE28870 BC025154 BC037645 AAH37645 BC089541 AAH89541 XM_006496628 XP_006496691 XM_006496629 XP_006496692 XM_006496630 XP_006496693 XM_006496631 XP_006496694 XM_006496632 XP_006496695 XM_011238743 XP_011237045 XM_011238744 XP_011237046 XR_373594 XR_373595 NM_001243062 NP_001229991 NM_001243063 NP_001229992 NM_009803 NP_033933 |
Function | Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. Cytoplasm. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Recruited to the cytoplasm by DNAJC7. |
Tissue Specificity | Predominantly expressed in liver. |
CAR1 (M-20) - sc-8539 from Santa Cruz Biotechnology
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CAR1/2 (T-20) - sc-8538 from Santa Cruz Biotechnology
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Anti-Constitutive androstane receptor antibody - ab55907 from Abcam
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Anti-NR1I3 (AB2) antibody produced in rabbit - AV37876 from Sigma-Aldrich
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Anti-NR1I3 (AB1) antibody produced in rabbit - AV37028 from Sigma-Aldrich
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NR1I3 antibody - C-terminal region (ARP37028_T100) - ARP37028_T100 from Aviva Systems Biology
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NR1I3 antibody - middle region (ARP37876_T100) - ARP37876_T100 from Aviva Systems Biology
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NR1I3 antibody - GTX113909 from GeneTex
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NR1I3 antibody - PAB5910 from Acris Antibodies
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NR1I3 Antibody - 28-609 from ProSci
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NR1I3 Antibody - 28-750 from ProSci
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NR1I3 Antibody - GWB-5E9D86 from Genway Biotech
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NR1I3 Antibody - GWB-9B5F1B from Genway Biotech
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MCAR1, Polyclonal Antibody - MBS643346 from MyBioSource
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MB67 Polyclonal Antibody - PA5-29866 from Thermo Fisher Scientific
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NR1I3-antibody-middle-region-AI11326 - AI11326 from Abgent, a WuXi AppTec company
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Polyclonal Antibody to Constitutive Androstane Receptor (CAR) - PAC422Mu01 from Cloud-clone
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NR1I3 / CAR antibody - TA341839 from Acris Antibodies
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NR1I3 antibody - C-terminal region : Biotin (ARP37028_T100-Biotin) - ARP37028_T100-Biotin from Aviva Systems Biology
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NR1I3 antibody - C-terminal region : FITC (ARP37028_T100-FITC) - ARP37028_T100-FITC from Aviva Systems Biology
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NR1I3 antibody - C-terminal region : HRP (ARP37028_T100-HRP) - ARP37028_T100-HRP from Aviva Systems Biology
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NR1I3 antibody - middle region : Biotin (ARP37876_T100-Biotin) - ARP37876_T100-Biotin from Aviva Systems Biology
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NR1I3 antibody - middle region : FITC (ARP37876_T100-FITC) - ARP37876_T100-FITC from Aviva Systems Biology
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NR1I3 antibody - middle region : HRP (ARP37876_T100-HRP) - ARP37876_T100-HRP from Aviva Systems Biology
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Constitutive Androstane Receptor (CAR) Polyclonal Antibody - CAU24293 from Biomatik
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