BCL2L2

Gene Symbol BCL2L2
Entrez Gene 599
Alt Symbol BCL-W, BCL2-L-2, BCLW, PPP1R51
Species Human
Gene Type protein-coding
Description BCL2-like 2
Other Description apoptosis regulator BCL-W|bcl-2-like protein 2|protein phosphatase 1, regulatory subunit 51
Swissprots A8K0F4 Q5U0H4 Q2M3U0 Q92843
Accessions EAW66169 Q92843 AA524030 AA741032 AK289519 BAF82208 BC021198 AAH21198 BC104789 AAI04790 BC113522 AAI13523 BP216712 BQ001111 BQ359913 BT019549 AAV38356 D87461 BAA19666 DA196433 DA288957 DA451936 HQ258092 ADR82846 U59747 AAB09055 NM_001199839 NP_001186768 NM_004050 NP_004041
Function Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX. {ECO:0000269|PubMed:8761287}.
Subcellular Location Mitochondrion membrane {ECO:0000269|PubMed:11423909, ECO:0000269|PubMed:12952938}; Peripheral membrane protein {ECO:0000269|PubMed:11423909, ECO:0000269|PubMed:12952938}. Note=Loosely associated with the mitochondrial membrane in healthy cells. During apoptosis, tightly bound to the membrane.
Tissue Specificity Expressed (at protein level) in a wide range of tissues with highest levels in brain, spinal cord, testis, pancreas, heart, spleen and mammary glands. Moderate levels found in thymus, ovary and small intestine. Not detected in salivary gland, muscle or liver. Also expressed in cell lines of myeloid, fibroblast and epithelial origin. Not detected in most lymphoid cell lines. {ECO:0000269|PubMed:11423909}.
Top Pathways MicroRNAs in cancer

Bcl-w (31H4) Rabbit mAb - 2724 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone 31H4
Western blot analysis of extracts from A673 and C2C12 cell lines, using Bcl-w (31H4) Rabbit mAb.

Bcl-w (H-139) - sc-11422 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Bcl-w (H-139): sc-11422. Immunofluorescence staining of methanol-fixed NIH/3T3 cells showing cytoplasmic localization.

Bcl-w (C-20) - sc-6418 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Bcl-w (C-20): sc-6418. Western blot analysis of human recombinant Bcl-w fusion protein.

Bcl-w (N-19) - sc-6172 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Bcl-w (N-19): sc-6172. Immunofluorescence staining of methanol-fixed NIH/3T3 cells showing cytoplasmic localization.

Bcl-w (G-21) - sc-130701 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
Bcl-w (G-21): sc-130701. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human hepatocarcinoma tissue showing cytoplasmic localization.

Anti-Bcl2L2 antibody - ab38629 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Bcl2L2 antibody (ab38629) + HL-60 cell lysate

Anti-Bcl2L2 antibody - ab124427 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab122427 at 1/100 dilution staining Bcl2L2 in Human fetal pancreas tissue by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.

Anti-BCL2L2 / Bcl-w Antibody - LS-C20889 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rat
Clonality Monoclonal

Anti-BCL2L2 / Bcl-w Antibody - LS-C20890 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rat
Clonality Monoclonal

Anti-BCL2L2 / Bcl-w Antibody - LS-C149188 from LifeSpan Bioscience

Prices $305.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-BCL2L2 / Bcl-w Antibody (C-Terminus, clone 12K13) - LS-C182764 from LifeSpan Bioscience

Prices $485.00
Sizes 250 µg
Host Mouse
Clonality Monoclonal
Clone 12K13

Anti-BCL2L2 / Bcl-w Antibody (aa1-100, AP) - LS-C275449 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCL2L2 / Bcl-w Antibody (Gly154) - LS-C177042 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Bcl-w (G154) pAb in extracts from COLO cells.

Anti-BCL2L2 / Bcl-w Antibody (aa122-171) - LS-C169492 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-BCL2L2 / Bcl-w Antibody - LS-C178870 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-BCL2L2 / Bcl-w Antibody - LS-C192412 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of BCL2L2 pAb in extracts from HL-60 cells.

Anti-BCL2L2 / Bcl-w Antibody (aa105-154) - LS-C200181 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HeLa cells using BCLW antibody.

Anti-BCL2L2 / Bcl-w Antibody - LS-C137199 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-BCL2L2 / Bcl-w Antibody (aa1-100, APC) - LS-C275451 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCL2L2 / Bcl-w Antibody (aa131-180) - LS-C119538 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of HepG2 cells, using BCLW Antibody. The picture on the right is treated with the synthesized peptide.

Anti-BCL2L2 / Bcl-w Antibody (aa1-100, FITC) - LS-C275453 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCL2L2 / Bcl-w Antibody (aa1-100, Biotin) - LS-C275452 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCL2L2 / Bcl-w Antibody (aa1-100, Azide-free, HRP) - LS-C275454 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCL2L2 / Bcl-w Antibody (aa1-100, PE) - LS-C275455 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCL2L2 / Bcl-w Antibody (clone 2E4) - LS-C196738 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E4
BCL2L2 monoclonal antibody (M01), clone 2E4. Western Blot analysis of BCL2L2 expression in human colon.
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