BCL2L2

Gene Symbol	BCL2L2
Entrez Gene	599
Alt Symbol	BCL-W, BCL2-L-2, BCLW, PPP1R51
Species	Human
Gene Type	protein-coding
Description	BCL2-like 2
Other Description	apoptosis regulator BCL-W|bcl-2-like protein 2|protein phosphatase 1, regulatory subunit 51
Swissprots	A8K0F4 Q5U0H4 Q2M3U0 Q92843
Accessions	EAW66169 Q92843 AA524030 AA741032 AK289519 BAF82208 BC021198 AAH21198 BC104789 AAI04790 BC113522 AAI13523 BP216712 BQ001111 BQ359913 BT019549 AAV38356 D87461 BAA19666 DA196433 DA288957 DA451936 HQ258092 ADR82846 U59747 AAB09055 NM_001199839 NP_001186768 NM_004050 NP_004041
Function	Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX. {ECO:0000269|PubMed:8761287}.
Subcellular Location	Mitochondrion membrane {ECO:0000269|PubMed:11423909, ECO:0000269|PubMed:12952938}; Peripheral membrane protein {ECO:0000269|PubMed:11423909, ECO:0000269|PubMed:12952938}. Note=Loosely associated with the mitochondrial membrane in healthy cells. During apoptosis, tightly bound to the membrane.
Tissue Specificity	Expressed (at protein level) in a wide range of tissues with highest levels in brain, spinal cord, testis, pancreas, heart, spleen and mammary glands. Moderate levels found in thymus, ovary and small intestine. Not detected in salivary gland, muscle or liver. Also expressed in cell lines of myeloid, fibroblast and epithelial origin. Not detected in most lymphoid cell lines. {ECO:0000269|PubMed:11423909}.
Top Pathways	MicroRNAs in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Bcl2L2 full length protein - ab132041 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human Bcl2L2 protein fragment - ab151806 from Abcam Category Protein Prices $188.00 Sizes 10 µg Source E. coli Species Human

Human Bcl2L2 protein fragment - ab174023 from Abcam Category Protein Prices $365.00 Sizes 100 µg Source E. coli Species Human

Human Bcl2L2 protein fragment - ab58944 from Abcam Category Protein Prices $1,079.00 Sizes 50 µl Source E. coli Species Human

Human Bcl2L2 protein fragment - ab117689 from Abcam Category Protein Prices $188.00 Sizes 5 µg Source E. coli Species Human

BCL2L2 / Bcl-w Antibody Blocking Peptide - LS-E2154 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BCL2L2 / Bcl-w Antibody Blocking Peptide - LS-E10608 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human BCL-W/BCL2L2 Protein - NBP2-34895 from Novus Biologicals Category Protein Prices $69.00, $149.00, $1,569.00 Sizes 5 µg, 25 µg, 1 mg Source E. coli Species Human

BCL-W/BCL2L2 Recombinant Protein - H00000599-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human BCL-W/BCL2L2 Protein - NBP1-37073 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E. coli Species Human

Bcl-w-Antibody-BH3-Domain-Specific-Blocking-peptide - BP1305a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Bcl-w-BH3-Domain-Peptide - SP1008a from Abgent, a WuXi AppTec company Category Peptide Prices $150.00 Sizes 1 mg

Recombinant Human Bcl-w (minus C-Terminus), CF - 824-BW-050 from R&D Systems Category Protein Source E. coli-derived, Ala2-Thr172, with a C-terminal 6-His tag

Recombinant Human Bcl-w Western Blot Standard Protein - WBC005 from R&D Systems Category Protein Prices $109.00 Sizes 100 µl Species Human

BCL2L2 Protein (OPPA02240) - OPPA02240 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human BCL2L2 protein - orb191276 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E. coli Species Human

Human BCL2L2 protein (His Tag) - orb80957 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 25 μg Species Human

Human BCL2L2 protein - orb244882 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human BCLW His tag protein - orb84307 from Biorbyt Category Protein Prices $570.00, $748.00 Sizes 50 μg, 100 μg Source E. coli Species Human

Human Bcl-w protein - orb223948 from Biorbyt Category Protein Prices $221.00, $357.00, $604.00, $850.00 Sizes 5 μg, 25 μg, 100 μg, 250 μg Species Human

BCL2L2 protein (His tag) - 80R-1239 from Fitzgerald Category Protein Prices $220.00 Sizes 100 µg Source E.coli

BCLW Blocking Peptide - abx062039 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Dog

Human Bcl2L2 Protein - abx065509 from Abbexa Category Protein Source E.coli Species Human

Bcl-2-like 2 (1-172, His-tag) - AR09337PU-L from Acris Antibodies Category Protein Prices $695.00 Sizes 500 µg Source E. coli Species Human

Bcl-2-like 2 (1-172, His-tag) - AR09337PU-N from Acris Antibodies Category Protein Prices $305.00 Sizes 100 µg Source E. coli Species Human

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