Reg3b

Gene Symbol Reg3b
Entrez Gene 18489
Alt Symbol HIP, PAP1, Pap, REG-III
Species Mouse
Gene Type protein-coding
Description regenerating islet-derived 3 beta
Other Description REG-3-beta|RegIII (beta)|pancreatitis-associated protein 1|reg III-beta|regenerating islet-derived protein 3-beta|regenerating islet-derived protein III-beta
Swissprots P35230
Accessions BAA18929 EDK99014 P35230 BC027525 AAH27525 D13509 BAA02727 D63359 BAA18928 NM_011036 NP_035166
Function Bactericidal C-type lectin which acts against several intestinal Gram-positive and Gram-negative bacteria. Lacks antibacterial activity against S.typhimurium. May play a role in protection against infection with S.enteritidis by inhibiting its translocation from the gut lumen into intestinal tissues and further extraintestinal tissues. {ECO:0000269|PubMed:21694778, ECO:0000269|PubMed:22252863}.
Subcellular Location Secreted. Note=Found in the apical region of pancreatic acinar cells. {ECO:0000250}.
Tissue Specificity Constitutively expressed in the small intestine, moderately in colon and at an extremely low level in healthy pancreas.

Reg3B Antibody - AF5110 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal
Reg3B was detected in immersion fixed frozen sections of mouse small intestine using 10 µg/mL Sheep Anti-Mouse Reg3B Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5110) overnight at 4 °C. Tissue was stained with the NorthernLights™ 557-conjugated Anti-Sheep IgG Secondary Antibody (red; Catalog # NL010) and counterstained with DAPI (blue). View our protocol for Fluorescent IHC Staining of Frozen Tissue Sections.

Hip Antibody [Unconjugated] - AF1568 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal

Reg3B Antibody (518630) - MAB5110 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Rat
Clonality Monoclonal
Clone 518630
Western blot shows lysates of mouse small intestine tissue. PVDF membrane was probed with 2 µg/mL of Mouse Reg3B Monoclonal Antibody (Catalog # MAB5110) followed by HRP-conjugated Anti-Rat IgG Secondary Antibody (Catalog # HAF005). A specific band was detected for Reg3B at approximately 17 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Hip Antibody [Biotin] - BAF1568 from Novus Biologicals

Prices $390.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Mouse Reg3B Antibody - AF5110 from R&D Systems

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Reg3B in Mouse Small Intestine. Reg3B was detected in immersion fixed frozen sections of mouse small intestine using 10 µg/mL Sheep Anti-Mouse Reg3B Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5110) overnight at 4 °C. Tissue was stained with the NorthernLights™ 557-conjugated Anti-Sheep IgG Secondary Antibody (red; Catalog # NL010 ) and counterstained with DAPI (blue). View our protocol for Fluorescent IHC Staining of Frozen Tissue Sections .

Mouse Reg3B Affinity Purified Polyclonal Ab, Sheep IgG - AF5110-SP from R&D Systems

Host Sheep
Clonality Polyclonal
Reg3B in Mouse Small Intestine. Reg3B was detected in immersion fixed frozen sections of mouse small intestine using 10 µg/mL Sheep Anti-Mouse Reg3B Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5110) overnight at 4 °C. Tissue was stained with the NorthernLights™ 557-conjugated Anti-Sheep IgG Secondary Antibody (red; Catalog # NL010) and counterstained with DAPI (blue). View our protocol for Fluorescent IHC Staining of Frozen Tissue Sections.

Mouse Reg3B Antibody - MAB5110 from R&D Systems

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Rat
Clone 518630
Detection of Mouse Reg3B by Western Blot. Western blot shows lysates of mouse small intestine tissue. PVDF membrane was probed with 2 µg/mL of Mouse Reg3B Monoclonal Antibody (Catalog # MAB5110) followed by HRP-conjugated Anti-Rat IgG Secondary Antibody (Catalog # HAF005 ). A specific band was detected for Reg3B at approximately 17 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1 .

Mouse Reg3B MAb (Clone 518630), Rat IgG2B - MAB5110-SP from R&D Systems

Host Rat
Clonality Monoclonal
Clone 518630
Detection of Mouse Reg3B by Western Blot. Western blot shows lysates of mouse small intestine tissue. PVDF membrane was probed with 2 µg/mL of Mouse Reg3B Monoclonal Antibody (Catalog # MAB5110) followed by HRP-conjugated Anti-Rat IgG Secondary Antibody (Catalog # HAF005). A specific band was detected for Reg3B at approximately 17 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Rat Reg3B Antibody - AF1996 from R&D Systems

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat

Rat Reg3B Affinity Purified Polyclonal Ab, Goat IgG - AF1996-SP from R&D Systems

Host Goat
Clonality Polyclonal

Rat Reg3B Biotinylated Antibody - BAF1996 from R&D Systems

Prices $390.00
Sizes 50 µg
Host Goat

Rat Reg3B Antibody - MAB1996 from R&D Systems

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clone 293523
Reg3B in Rat Pancreas. Reg3B was detected in perfusion fixed frozen sections of rat pancreas using Mouse Anti-Rat Reg3B Monoclonal Antibody (Catalog # MAB1996) at 25 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002 ) and counterstained with hematoxylin (blue). Specific labeling was localized to the cytoplasm of exocrine cells. View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections .

Rat Reg3B MAb (Clone 293523), Mouse IgG1 - MAB1996-SP from R&D Systems

Host Mouse
Clonality Monoclonal
Clone 293523
Reg3B in Rat Pancreas. Reg3B was detected in perfusion fixed frozen sections of rat pancreas using Mouse Anti-Rat Reg3B Monoclonal Antibody (Catalog # MAB1996) at 25 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). Specific labeling was localized to the cytoplasm of exocrine cells. View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.

Anti-Regenerating Islet Derived Protein 3 Gamma (REG3g), Mouse - 20-5053 from ARP American Research Products

Prices $359.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Polyclonal Antibody to Regenerating Islet Derived Protein 3 Beta (REG3b) - PAK541Mu01 from Uscn Life Science Inc.

Host Rabbit
Clonality Polyclonal

Polyclonal Antibody to Regenerating Islet Derived Protein 3 Beta (REG3b) - PAK541Mu02 from Uscn Life Science Inc.

Host Rabbit
Clonality Polyclonal

Monoclonal Antibody to Regenerating Islet Derived Protein 3 Beta (REG3b) - MAK541Ra21 from Uscn Life Science Inc.

Host Mouse
Clonality Monoclonal

Polyclonal Antibody to Regenerating Islet Derived Protein 3 Beta (REG3b) - PAK541Ra01 from Uscn Life Science Inc.

Host Rabbit
Clonality Polyclonal

PAP (Prostatic Acid Phosphatase) - CH23019 from Neuromics

Prices $295.00
Sizes 200 µl
Host Chicken
Clonality Polyclonal
Images: Tissue sections through a 10%-formalin fixed adult mouse. Sections were examined for PAP positive dorsal root ganglion sensory neurons. Secondary antibodies ( fluorescein-labeled goat anti-chicken IgY, Neuromics Cat. #CH23101 )  were used at a concentration of 1:500.

Polyclonal Antibody to Hedgehog Interacting Protein (HHIP) - PAC524Mu01 from Cloud-clone

Host Rabbit
Clonality Polyclonal

Polyclonal Antibody to Hedgehog Interacting Protein (HHIP) - PAC524Mu02 from Cloud-clone

Host Rabbit
Clonality Polyclonal
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