| Gene Symbol |
Reg3b
|
| Entrez Gene |
18489
|
| Alt Symbol |
HIP, PAP1, Pap, REG-III
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
regenerating islet-derived 3 beta
|
| Other Description |
REG-3-beta|RegIII (beta)|pancreatitis-associated protein 1|reg III-beta|regenerating islet-derived protein 3-beta|regenerating islet-derived protein III-beta
|
| Swissprots |
P35230
|
| Accessions |
BAA18929 EDK99014 P35230 BC027525 AAH27525 D13509 BAA02727 D63359 BAA18928 NM_011036 NP_035166
|
| Function |
Bactericidal C-type lectin which acts against several intestinal Gram-positive and Gram-negative bacteria. Lacks antibacterial activity against S.typhimurium. May play a role in protection against infection with S.enteritidis by inhibiting its translocation from the gut lumen into intestinal tissues and further extraintestinal tissues. {ECO:0000269|PubMed:21694778, ECO:0000269|PubMed:22252863}.
|
| Subcellular Location |
Secreted. Note=Found in the apical region of pancreatic acinar cells. {ECO:0000250}.
|
| Tissue Specificity |
Constitutively expressed in the small intestine, moderately in colon and at an extremely low level in healthy pancreas.
|