Dpp4

Gene Symbol	Dpp4
Entrez Gene	13482
Alt Symbol	Cd26, Dpp-4, THAM
Species	Mouse
Gene Type	protein-coding
Description	dipeptidylpeptidase 4
Other Description	DPP IV|T-cell activation antigen CD26|dipeptidyl peptidase 4|dipeptidyl peptidase IV|thymocyte-activating molecule
Swissprots	Q3U514 P28843
Accessions	AAA82213 EDL26985 EDL26986 P28843 AK040409 AK085370 BAC39434 AK153591 AK153939 BAE32266 AK163085 BAE37187 AK164775 BC022183 AAH22183 X58384 CAA41274 XM_006498691 XP_006498754 XM_006498692 XP_006498755 XM_006498693 XP_006498756 XM_011239274 XP_011237576 NM_001159543 NP_001153015 NM_010074 NP_034204
Function	Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF- kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth fact
Subcellular Location	Dipeptidyl peptidase 4 soluble form: Secreted. Note=Detected in the serum and the seminal fluid. {ECO:0000250}.
Top Pathways	Protein digestion and absorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Recombinant Mouse DPPIV/CD26, CF - 954-SE-010 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Ser29-His760, with a C-terminal 9-His tag

Mouse CD26 (Fc Tag) protein - orb179713 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 10 μg, 20 μg Source Human Cells Species Mouse

Mouse DPP4 Protein - abx066344 from Abbexa Category Protein Source E.coli Species Mouse

Mouse DPP4 Protein - abx066346 from Abbexa Category Protein Source E.coli Species Mouse

Dipeptidyl Peptidase IV (DPP4), Mouse - 20-7281 from ARP American Research Products Category Protein Prices $519.00 Sizes 50 µg Source E.coli Species Mouse

Dipeptidyl Peptidase IV (DPP4), Mouse - 20-7282 from ARP American Research Products Category Protein Prices $489.00 Sizes 50 µg Source E.coli Species Mouse

Recombinant Mouse Dipeptidylpeptidase 4, His-tagged - Dpp4-413M from Creative Biomart Category Protein Source Murine myeloma cellline, NS0-derived

Recombinant Mouse Dpp4, Fc-tagged - Dpp4-120M from Creative Biomart Category Protein Source Human Cells Species Mouse

Mouse DPP4 / CD26 Protein (His Tag) - 50718-M08H-10 from Sino Biological Category Protein Source Human Cells Species Mouse

Mouse DPP4 / CD26 Protein (Fc Tag) - 50718-M01H-20 from Sino Biological Category Protein Source Human Cells Species Mouse

Recombinant Dipeptidyl Peptidase IV (DPP4) - RPA884Mu01 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Dipeptidyl Peptidase IV (DPP4) - RPA884Mu02 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Mouse Dipeptidyl peptidase 4(Dpp4) - CSB-YP007139MO CSB-EP007139MO CSB-BP007139MO CSB-MP007139MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

Recombinant Mouse DPPIV/CD26 Protein, CF - 954-SE from R&D Systems Category Protein Prices $329.00 Sizes 10 µg Source Mouse myeloma cell line, NS0-derived Ser29-His760, with a C-terminal 9-His tag Species Mouse

Dipeptidyl Peptidase IV (DPP4) - RPU141206 from Biomatik Category Protein Prices $247.50, $495.00, $742.50 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Mouse

Dipeptidyl Peptidase IV (DPP4) - RPU141208 from Biomatik Category Protein Prices $231.00, $462.00, $693.00 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Mouse

Mouse CD26 (His Tag) protein - orb232621 from Biorbyt Category Protein Prices $510.00, $1,088.00 Sizes 10 μg, 50 μg Species Mouse

Recombinant Mouse DPP4 Protein - DPP4-4794M from Creative Biomart Category Protein Source Mammalian Cells Species Mouse

Recombinant Mouse Dpp4 protein, His-tagged - Dpp4-415M from Creative Biomart Category Protein Source HEK293 Species Mouse

Mouse Dpp4 protein - orb54715 from Biorbyt Category Protein Prices $859.00, $910.00, $1,190.00 Sizes 10 μg, 50 μg, 100 μg Species Mouse

Recombinant Dipeptidyl Peptidase IV (DPP4) - RPU41208 from Biomatik Category Protein Prices $185.00, $378.00, $578.00, $688.80 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Mouse

Recombinant Dipeptidyl Peptidase IV (DPP4) - RPU41206 from Biomatik Category Protein Prices $198.00, $387.00, $619.00, $738.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Mouse

DPP4 Recombinant Protein (OPCD02786) - OPCD02786 from Aviva Systems Biology Category Protein Source E.coli Species Mouse

DPP4 Recombinant Protein (OPCD02788) - OPCD02788 from Aviva Systems Biology Category Protein Source E.coli Species Mouse

Mouse DPP4 / CD26 Protein (Fc Tag) - 50718-M01H from ABclonal Category Protein Prices $178.00, $298.00 Sizes 10 µg, 20 µg Source Human Cells Species Mouse

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