Dpp4

Gene Symbol Dpp4
Entrez Gene 13482
Alt Symbol Cd26, Dpp-4, THAM
Species Mouse
Gene Type protein-coding
Description dipeptidylpeptidase 4
Other Description DPP IV|T-cell activation antigen CD26|dipeptidyl peptidase 4|dipeptidyl peptidase IV|thymocyte-activating molecule
Swissprots Q3U514 P28843
Accessions AAA82213 EDL26985 EDL26986 P28843 AK040409 AK085370 BAC39434 AK153591 AK153939 BAE32266 AK163085 BAE37187 AK164775 BC022183 AAH22183 X58384 CAA41274 XM_006498691 XP_006498754 XM_006498692 XP_006498755 XM_006498693 XP_006498756 XM_011239274 XP_011237576 NM_001159543 NP_001153015 NM_010074 NP_034204
Function Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF- kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth fact
Subcellular Location Dipeptidyl peptidase 4 soluble form: Secreted. Note=Detected in the serum and the seminal fluid. {ECO:0000250}.
Top Pathways Protein digestion and absorption

CD26 (T-19) - sc-7044 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CD26 antibody [H207-1082] (Biotin) - ab42897 from Abcam

Prices $370.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone H207-1082

Anti-CD26 antibody [H207-1082] (FITC) - ab42898 from Abcam

Prices $370.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone H207-1082

Anti-CD26 antibody [H207-1082] (Phycoerythrin) - ab53433 from Abcam

Prices $185.00
Sizes 50 tests
Host Rat
Clonality Monoclonal
Clone H207-1082

DPPIV/CD26 Antibody [Unconjugated] - AF954 from Novus Biologicals

Prices $99.00, $365.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Simple Western lane view shows lysates of rat lung tissue and mouse thymus tissue, loaded at 0.2 mg/mL. A specific band was detected for DPPIV/CD26 at approximately 144-169 kDa (as indicated) using 5 µg/mL of Goat Anti-Mouse DPPIV/CD26 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF954) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

DPPIV/CD26 Antibody - NB100-61658 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: DPPIV/CD26 Antibody [NB100-61658] - (0.3ug/ml) staining of Rat Lung lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

DPPIV/CD26 Antibody (RM0223-9J28) - NBP2-12154 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone RM0223-9J28

DPPIV/CD26 Antibody (H207-1082) - NB100-62997 from Novus Biologicals

Prices $279.00
Sizes 125 µg
Host Rat
Clonality Monoclonal
Clone H207-1082
Flow Cytometry: DPPIV/CD26 Antibody (H207-1082) [NB100-62997] - Analysis using the Biotin conjugate of NB100-62997. Staining of mouse peripheral blood lymphocytes.

DPPIV/CD26 Antibody [Biotin] - BAF954 from Novus Biologicals

Prices $390.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

DPPIV/CD26 Antibody (155202) [Allophycocyanin] - FAB9541A from Novus Biologicals

Prices $309.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 155202

DPPIV/CD26 Antibody (155202) [Phycoerythrin] - FAB9541P from Novus Biologicals

Prices $249.00
Sizes 100 tests
Host Rat
Clonality Monoclonal
Clone 155202
Mouse thymocytes were stained with Rat Anti-Mouse DPPIV/CD26 PE-conjugated Monoclonal Antibody (Catalog # FAB9541P, filled histogram) or isotype control antibody (Catalog # IC006P, open histogram). View our protocol for Staining Membrane-associated Proteins.

DPPIV/CD26 Antibody (155202) [Fluorescein] - FAB9541F from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone 155202

DPPIV/CD26 Antibody (H194-112) [PerCP/Cy5.5] - NBP2-00001 from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone H194-112
Flow Cytometry: CD26 Antibody (H194-112) [PerCP/Cy5.5] [NBP2-00001] - Staining of C57BL/6 thymocytes with 0.5 ug of Rat IgG2a kappa Isotype Control PerCP-Cy5.5 (NBP1-42840) (blue histogram) or 0.5 ug of Anti-Mouse CD26 PerCP-Cy5.5 (purple histogram). Total viable cells were used for analysis.

DPPIV/CD26 Antibody (H207-1082) [Biotin] - NB100-63642 from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone H207-1082

DPPIV/CD26 Antibody (H207-1082) [FITC] - NB100-63643 from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone H207-1082

DPPIV/CD26 Antibody (H207-1082) [PerCP] - NB100-62997PCP from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone H207-1082

DPPIV/CD26 Antibody (H207-1082) [Allophycocyanin] - NB100-62997APC from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone H207-1082

DPPIV/CD26 Antibody (H207-1082) [PE] - NB100-62997PE from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone H207-1082

DPPIV/CD26 Antibody (H207-1082) [DyLight 680] - NB100-62997FR from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone H207-1082

DPPIV/CD26 Antibody (H207-1082) [DyLight 488] - NB100-62997G from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone H207-1082

DPPIV/CD26 Antibody (H207-1082) [DyLight 755] - NB100-62997IR from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone H207-1082

DPPIV/CD26 Antibody (H207-1082) [DyLight 350] - NB100-62997UV from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone H207-1082

DPPIV/CD26 Antibody (H207-1082) [DyLight 405] - NB100-62997V from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone H207-1082

DPPIV/CD26 Antibody (H207-1082) [7C] - NB100-62997V2 from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone H207-1082

DPPIV/CD26 Antibody (H207-1082) [Alexa Fluor (R) 700] - NB100-62997AF700 from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone H207-1082
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