Crbn

Gene Symbol Crbn
Entrez Gene 58799
Alt Symbol 2610203G15Rik, 2900045O07Rik, AF229032, AW108261, piL
Species Mouse
Gene Type protein-coding
Description cereblon
Other Description novel lethal|protein PiL|protein cereblon
Swissprots Q80XJ1 Q6IS49 Q8C6B7 Q8BP45 Q5RJV6 Q8C7D2 Q3TVC2 Q9JKR4
Accessions EDK99399 EDK99400 EDK99401 Q8C7D2 AF229032 AAF35895 AK032836 AK050557 BAC34322 AK075959 AK076144 BAC36214 AK077707 BAC36970 AK141428 AK160219 BAE35697 BC033458 BC046967 AAH46967 BC069905 AAH69905 BC086488 AAH86488 BQ749260 CD766233 CJ073661 NM_021449 NP_067424 NM_175357 NP_780566
Function Substrate recognition component of a DCX (DDB1-CUL4-X- box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as MEIS2. Normal degradation of key regulatory proteins is required for normal limb outgrowth and expression of the fibroblast growth factor FGF8 (By similarity). May play a role in memory and learning by regulating the assembly and neuronal surface expression of large-conductance calcium-activated potassium channels in brain regions involved in memory and learning via its interaction with KCNT1 (By similarity). {ECO:0000250|UniProtKB:Q96SW2, ECO:0000305}.
Subcellular Location Cytoplasm {ECO:0000250|UniProtKB:Q96SW2}. Nucleus {ECO:0000250|UniProtKB:Q96SW2}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Tissue Specificity Highly expressed in brain. {ECO:0000269|PubMed:20131966}.

Cereblon (CRBN), Mouse, ELISA Kit - SEG676Mu from ARP American Research Products

Category ELISA Kit
Prices $740.00
Sizes 96 t
Sensitivity 0.057ng/mL
Range 0.156-10ng/mL

Protein cereblon, Crbn, Mouse, ELISA Kit - E12793m from ARP American Research Products

Category ELISA Kit
Prices $736.00
Sizes 96 t

Mouse Cereblon (CRBN) ELISA Kit - EKU03078 from Biomatik

Category ELISA Kit
Prices $756.00, $3,326.00, $6,048.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 0.057 ng/mL
Range 0.156-10 ng/mL

Mouse Cereblon ELISA Kit - abx153810 from Abbexa

Category ELISA Kit
Sensitivity 0.057 ng/ml
Range 0.156 ng/ml - 10 ng/ml

Cereblon (CRBN), Mouse, ELISA Kit - DL-CRBN-Mu from ARP American Research Products

Category ELISA Kit
Prices $685.00
Sizes 96 t
Range 0.156-10 ng/mL

Mouse CRBN ELISA Kit - abx571794 from Abbexa

Category ELISA Kit
Sensitivity 0.057 ng/ml
Range 0.156 ng/ml - 10 ng/ml

Mouse Crbn ELISA Kit - E048019 from Biobool

Category ELISA Kit

CRBN ELISA Kit (Mouse) (OKCD02462) - OKCD02462 from Aviva Systems Biology

Category ELISA Kit
Prices $555.00
Sizes 10 ng
Sensitivity 0.057 ng/mL
Range 0.156-10 ng/mL

Protein cereblon, ELISA Kit - MBS760148 from MyBioSource

Category ELISA Kit
Prices $295.00, $390.00, $1,615.00, $3,015.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.188ng/ml
Range 0.312-20ng/ml

cereblon, ELISA Kit - MBS2886542 from MyBioSource

Category ELISA Kit
Prices $430.00, $570.00, $2,515.00, $4,520.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cereblon (CRBN), ELISA Kit - MBS454369 from MyBioSource

Category ELISA Kit
Prices $425.00, $560.00, $2,480.00, $4,820.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity <0.057ng/mL
Range 0.156-10ng/mL
Search more