Crbn

Gene Symbol Crbn
Entrez Gene 58799
Alt Symbol 2610203G15Rik, 2900045O07Rik, AF229032, AW108261, piL
Species Mouse
Gene Type protein-coding
Description cereblon
Other Description novel lethal|protein PiL|protein cereblon
Swissprots Q80XJ1 Q6IS49 Q8C6B7 Q8BP45 Q5RJV6 Q8C7D2 Q3TVC2 Q9JKR4
Accessions EDK99399 EDK99400 EDK99401 Q8C7D2 AF229032 AAF35895 AK032836 AK050557 BAC34322 AK075959 AK076144 BAC36214 AK077707 BAC36970 AK141428 AK160219 BAE35697 BC033458 BC046967 AAH46967 BC069905 AAH69905 BC086488 AAH86488 BQ749260 CD766233 CJ073661 NM_021449 NP_067424 NM_175357 NP_780566
Function Substrate recognition component of a DCX (DDB1-CUL4-X- box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as MEIS2. Normal degradation of key regulatory proteins is required for normal limb outgrowth and expression of the fibroblast growth factor FGF8 (By similarity). May play a role in memory and learning by regulating the assembly and neuronal surface expression of large-conductance calcium-activated potassium channels in brain regions involved in memory and learning via its interaction with KCNT1 (By similarity). {ECO:0000250|UniProtKB:Q96SW2, ECO:0000305}.
Subcellular Location Cytoplasm {ECO:0000250|UniProtKB:Q96SW2}. Nucleus {ECO:0000250|UniProtKB:Q96SW2}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Tissue Specificity Highly expressed in brain. {ECO:0000269|PubMed:20131966}.

Recombinant Cereblon (CRBN) - RPG676Mu01 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant Cereblon (CRBN) - RPG676Mu02 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant Mouse Protein cereblon(Crbn) - CSB-YP806030MO CSB-EP806030MO CSB-BP806030MO CSB-MP806030MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Recombinant Mouse CRBN Protein - CRBN-3883M from Creative Biomart

Category Protein
Source Mammalian Cells
Species Mouse

Mouse Crbn protein - orb54199 from Biorbyt

Category Protein
Prices $213.00, $408.00, $612.00, $680.00, $1,122.00, $1,777.00
Sizes 10 μg, 50 μg, 100 μg, 200 μg, 500 μg, 1 mg
Species Mouse

Protein cereblon (Crbn), Recombinant Protein - MBS1387741 from MyBioSource

Category Protein
Prices $1,225.00, $1,225.00, $1,455.00, $1,455.00, $1,965.00, $1,965.00, $2,425.00, $2,425.00, $2,425.00, $3,880.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 50 µg (Mammalian-Cell), 500 µg (Yeast), 1 mg (E-Coli), 100 µg (Baculovirus), 100 µg (Mammalian-Cell), 1 mg (Yeast), 500 µg (Baculovirus), 1 mg (Baculovirus)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse

CRBN Recombinant Protein (Mouse) (OPCA04681) - OPCA04681 from Aviva Systems Biology

Category Protein
Species Mouse

Recombinant Mouse Protein cereblon (Crbn) - RPC25449 from Biomatik

Category Protein
Prices $275.00, $503.00, $2,499.00
Sizes 50 µg, 100 µg, 1 mg
Source Yeast
Species Mouse
Search more