ADIPOQ

Gene Symbol	ADIPOQ
Entrez Gene	9370
Alt Symbol	ACDC, ACRP30, ADIPQTL1, ADPN, APM-1, APM1, GBP28
Species	Human
Gene Type	protein-coding
Description	adiponectin, C1Q and collagen domain containing
Other Description	30 kDa adipocyte complement-related protein|adipocyte complement-related 30 kDa protein|adiponectin|adipose most abundant gene transcript 1 protein|adipose specific collagen-like factor|gelatin-binding protein 28
Swissprots	Q58EX9 Q15848
Accessions	BAA86716 CAB52413 CAT82843 CBL63519 EAW78165 Q15848 AK291525 BAF84214 AK312868 BAG35720 AL832470 AX767959 CAE01099 BC054496 AAH54496 BC096308 AAH96308 BC096309 AAH96309 BC096310 AAH96310 BC096311 AAH96311 D45371 BAA08227 EU420013 ABZ10942 XM_011513324 XP_011511626 NM_001177800 NP_001171271 NM_004797 NP_004788
Function	Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. {ECO:0000269|PubMed:11479627}.
Subcellular Location	Secreted.
Tissue Specificity	Synthesized exclusively by adipocytes and secreted into plasma.
Top Pathways	Adipocytokine signaling pathway, Type II diabetes mellitus, PPAR signaling pathway, Non-alcoholic fatty liver disease (NAFLD), AMPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Adiponectin full length protein - ab157078 from Abcam Category Protein Prices $465.00 Sizes 50 µg Source HEK 293 cells Species Human

Active human Adiponectin full length protein - ab50219 from Abcam Category Protein Prices $110.00, $257.00 Sizes 5 µg, 25 µg Source E. coli Species Human

Active human Adiponectin peptide - ab39918 from Abcam Category Peptide Prices $181.00 Sizes 50 µg Species Human

Active human Adiponectin protein fragment - ab78588 from Abcam Category Protein Prices $257.00 Sizes 5 µg Source E. coli Species Human

Active human Adiponectin protein fragment - ab190961 from Abcam Category Protein Source E. coli Species Human

Active mouse Adiponectin protein fragment - ab134631 from Abcam Category Protein Prices $110.00, $316.00 Sizes 5 µg, 25 µg Source High-5 insect cells Species Mouse

Active mouse Adiponectin protein fragment - ab50177 from Abcam Category Protein Prices $110.00, $257.00 Sizes 5 µg, 25 µg Source E. coli Species Mouse

Dog Adiponectin full length protein - ab108945 from Abcam Category Protein Prices $252.00 Sizes 10 µg Source HEK 293 cells Species Dog

Dog Adiponectin protein fragment - ab109043 from Abcam Category Protein Prices $309.00 Sizes 10 µg Source HEK 293 cells Species Dog

Human Adiponectin (mutated C36 A) full length protein - ab109034 from Abcam Category Protein Source HEK 293 cells Species Human

Human Adiponectin full length protein - ab13882 from Abcam Category Protein Source E. coli Species Human

Human Adiponectin full length protein - ab152086 from Abcam Category Protein Prices $188.00 Sizes 10 µg Source HEK 293 cells Species Human

Human Adiponectin full length protein - ab28159 from Abcam Category Protein Prices $564.00 Sizes 100 µg Source HEK 293 cells Species Human

Human Adiponectin full length protein - ab51294 from Abcam Category Protein Prices $297.00, $1,210.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Human Adiponectin full length protein - ab54482 from Abcam Category Protein Prices $309.00 Sizes 25 µg Source E. coli Species Human

Human Adiponectin protein fragment - ab157291 from Abcam Category Protein Prices $297.00 Sizes 10 µg Source HEK 293 cells Species Human

Human Adiponectin protein fragment - ab180294 from Abcam Category Protein Prices $357.00 Sizes 100 µg Source E. coli Species Human

Human Adiponectin protein fragment - ab67744 from Abcam Category Protein Prices $196.00 Sizes 10 µg Source E. coli Species Human

Human Adiponectin recombinant protein - ab50222 from Abcam Category Protein Prices $110.00, $252.00 Sizes 5 µg, 25 µg Source E. coli Species Human

Mouse Adiponectin (mutated C39 A) full length protein - ab94676 from Abcam Category Protein Source HEK 293 cells Species Mouse

Mouse Adiponectin full length protein - ab54483 from Abcam Category Protein Source E. coli Species Mouse

Mouse Adiponectin full length protein - ab62957 from Abcam Category Protein Source E. coli Species Mouse

Mouse Adiponectin peptide - ab95053 from Abcam Category Peptide

Mouse Adiponectin protein fragment - ab157283 from Abcam Category Protein Source HEK 293 cells Species Mouse

Mouse Adiponectin protein fragment - ab51300 from Abcam Category Protein Source E. coli Species Mouse

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