ADIPOQ

Gene Symbol ADIPOQ
Entrez Gene 9370
Alt Symbol ACDC, ACRP30, ADIPQTL1, ADPN, APM-1, APM1, GBP28
Species Human
Gene Type protein-coding
Description adiponectin, C1Q and collagen domain containing
Other Description 30 kDa adipocyte complement-related protein|adipocyte complement-related 30 kDa protein|adiponectin|adipose most abundant gene transcript 1 protein|adipose specific collagen-like factor|gelatin-binding protein 28
Swissprots Q58EX9 Q15848
Accessions BAA86716 CAB52413 CAT82843 CBL63519 EAW78165 Q15848 AK291525 BAF84214 AK312868 BAG35720 AL832470 AX767959 CAE01099 BC054496 AAH54496 BC096308 AAH96308 BC096309 AAH96309 BC096310 AAH96310 BC096311 AAH96311 D45371 BAA08227 EU420013 ABZ10942 XM_011513324 XP_011511626 NM_001177800 NP_001171271 NM_004797 NP_004788
Function Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. {ECO:0000269|PubMed:11479627}.
Subcellular Location Secreted.
Tissue Specificity Synthesized exclusively by adipocytes and secreted into plasma.
Top Pathways Adipocytokine signaling pathway, Type II diabetes mellitus, PPAR signaling pathway, Non-alcoholic fatty liver disease (NAFLD), AMPK signaling pathway

Acrp30 CRISPR/Cas9 KO Plasmid (h) - sc-401327 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Acrp30 HDR Plasmid (h) - sc-401327-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Acrp30 Double Nickase Plasmid (h) - sc-401327-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Acrp30 Double Nickase Plasmid (h2) - sc-401327-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Acrp30 CRISPR Activation Plasmid (h) - sc-401327-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Acrp30 CRISPR Activation Plasmid (h2) - sc-401327-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Acrp30 Lentiviral Activation Particles (h) - sc-401327-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Acrp30 Lentiviral Activation Particles (h2) - sc-401327-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Acrp30 siRNA (h) - sc-43600 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Acrp30 shRNA Plasmid (h) - sc-43600-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Acrp30 shRNA (h) Lentiviral Particles - sc-43600-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Adiponectin/Acrp30 RNAi - H00009370-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU150631 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1952 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1952 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ADIPOQ siRNA (Human) - CRH6206 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ADIPOQ - MBS8224511 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ADIPOQ (NM_004797.3) - SHH232454 from Creative biogene

Category siRNA
Species Reactivities Human

Human ADIPOQ siRNA - orb266708 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ADIPOQ shRNA Plasmid (Human) - CHH6206 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ADIPOQ miRNA 3'UTR clone - MiUTR4H-TG00176 from Creative biogene

Species Reactivities Human
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