Gene Symbol | Timp3 |
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Entrez Gene | 21859 |
Alt Symbol | Timp-3 |
Species | Mouse |
Gene Type | protein-coding |
Description | tissue inhibitor of metalloproteinase 3 |
Other Description | metalloproteinase inhibitor 3|tissue inhibitor of metalloproteinases 3 |
Swissprots | P39876 Q91WL9 |
Accessions | AAA85860 EDL21437 EDL21438 P39876 AB041611 BAA95094 AK082483 AK083905 BAC39055 AK084069 AK128943 AK147847 BAE28178 AY622855 AAT46410 BC014713 AAH14713 BE651900 BY439696 L19622 AAC37669 L27424 AAA40447 Z30970 CAA83218 Z31358 NM_011595 NP_035725 |
Function | Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. |
Subcellular Location | Secreted, extracellular space, extracellular matrix. |
Tissue Specificity | Highest levels are found in kidney, lung and brain followed by ovary and uterus. Low levels are found in bone. |
Top Pathways | MicroRNAs in cancer, Proteoglycans in cancer |
Mouse TIMP3 Protein - abx069338 from Abbexa
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Tissue Inhibitors Of Metalloproteinase 3 (TIMP3), Mouse - 20-6312 from ARP American Research Products
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Recombinant Mouse Metalloproteinase inhibitor 3(Timp3) - CSB-YP023562MO CSB-EP023562MO CSB-BP023562MO CSB-MP023562MO from Cusabio
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Recombinant Mouse TIMP3 Protein - TIMP3-16800M from Creative Biomart
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TIMP3 Recombinant Protein (OPCD07463) - OPCD07463 from Aviva Systems Biology
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Metalloproteinase inhibitor 3 (Timp3), Recombinant Protein - MBS949651 from MyBioSource
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