Gene Symbol | Hsd11b2 |
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Entrez Gene | 25117 |
Alt Symbol | - |
Species | Rat |
Gene Type | protein-coding |
Description | hydroxysteroid 11-beta dehydrogenase 2 |
Other Description | 11-DH2|11-beta-HSD2|11-beta-hydroxysteroid dehydrogenase type 2|Hydroxysteroid dehydrogenase, 11 beta type 2|NAD-dependent 11-beta-hydroxysteroid dehydrogenase|corticosteroid 11-beta-dehydrogenase isozyme 2 |
Swissprots | P50233 |
Accessions | AAX45243 EDL92380 P50233 BC087023 AAH87023 U22424 AAA87007 XM_006255445 XP_006255507 NM_017081 NP_058777 |
Function | Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids. |
Subcellular Location | Microsome. Endoplasmic reticulum {ECO:0000305}. |
Tissue Specificity | Highly expressed in kidney, adrenal gland and distal colon. Detected at much lower levels in lung. |
Top Pathways | Steroid hormone biosynthesis, Aldosterone-regulated sodium reabsorption |
Corticosteroid 11-beta-dehydrogenase isozyme 2 (HSD11B2), Rat, ELISA Kit - E02C2305 from ARP American Research Products
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11-Beta-Hydroxysteroid Dehydrogenase Type 2, ELISA Kit - MBS073678 from MyBioSource
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ELISA Kit for 11-Beta-Hydroxysteroid Dehydrogenase Type 2 (HSD11b2) - SEF183Ra from Cloud-clone
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Rat 11-Beta-Hydroxysteroid Dehydrogenase Type 2 (HSD11b2) ELISA Kit - EKU02005 from Biomatik
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Rat HSD11b2 ELISA Kit - abx155645 from Abbexa
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Rat Hsd11b2 ELISA Kit - E081292 from Biobool
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HSD11B2 ELISA Kit (Rat) (OKCD01261) - OKCD01261 from Aviva Systems Biology
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