Hsd11b2

Gene Symbol	Hsd11b2
Entrez Gene	25117
Alt Symbol	-
Species	Rat
Gene Type	protein-coding
Description	hydroxysteroid 11-beta dehydrogenase 2
Other Description	11-DH2|11-beta-HSD2|11-beta-hydroxysteroid dehydrogenase type 2|Hydroxysteroid dehydrogenase, 11 beta type 2|NAD-dependent 11-beta-hydroxysteroid dehydrogenase|corticosteroid 11-beta-dehydrogenase isozyme 2
Swissprots	P50233
Accessions	AAX45243 EDL92380 P50233 BC087023 AAH87023 U22424 AAA87007 XM_006255445 XP_006255507 NM_017081 NP_058777
Function	Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
Subcellular Location	Microsome. Endoplasmic reticulum {ECO:0000305}.
Tissue Specificity	Highly expressed in kidney, adrenal gland and distal colon. Detected at much lower levels in lung.
Top Pathways	Steroid hormone biosynthesis, Aldosterone-regulated sodium reabsorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Recombinant 11-Beta-Hydroxysteroid Dehydrogenase Type 2 (HSD11b2) - RPF183Ra01 from Cloud-clone Category Protein Source E.coli Species Rat

Recombinant Rat Corticosteroid 11-beta-dehydrogenase isozyme 2(Hsd11b2) - CSB-YP010765RA CSB-EP010765RA CSB-BP010765RA CSB-MP010765RA from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Rat

11-Beta-Hydroxysteroid Dehydrogenase Type 2 Protein (Recombinant) - abx167592 from Abbexa Category Protein Source Rat Species Rat

Recombinant Rat HSD11B2 Protein - HSD11B2-2921R from Creative Biomart Category Protein Source Mammalian Cells Species Rat

Recombinant 11-Beta-Hydroxysteroid Dehydrogenase Type 2 (HSD11b2) - RPU52893 from Biomatik Category Protein Prices $192.00, $392.00, $600.00, $715.04 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Rat

HSD11B2 Recombinant Protein (OPCD03986) - OPCD03986 from Aviva Systems Biology Category Protein Source E.coli Species Rat

Corticosteroid 11-beta-dehydrogenase isozyme 2 (Hsd11b2), Recombinant Protein - MBS1027875 from MyBioSource Category Protein Prices $1,170.00, $1,170.00, $1,390.00, $1,390.00, $1,880.00, $1,880.00, $2,345.00, $2,345.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Rat

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