MYD88

Gene Symbol MYD88
Entrez Gene 4615
Alt Symbol MYD88D
Species Human
Gene Type protein-coding
Description myeloid differentiation primary response 88
Other Description myeloid differentiation primary response gene (88)|myeloid differentiation primary response protein MyD88
Swissprots J3KPU4 B4DKH8 Q99836 B4DKU4 Q53XS7 B4DQ72 J3KQJ6 B4DQ60 J3KQ87 P78397
Accessions EAW64520 EAW64521 Q99836 AB446470 BAG55247 AK097983 AK124685 AK296570 BAG59190 AK296716 BAG59306 AK298650 BAG60822 AK298666 BAG60834 AK300051 BAG61860 AK300448 BAG62170 AK304676 BAG65448 AL832906 BC013589 AAH13589 BP242808 BP339466 BT007376 AAP36040 BX537602 DC350705 EU831951 ACE87392 EU832045 ACE86707 U70451 AAB49967 U84408 AAC50954 XM_005265172 XP_005265229 XM_006713170 XP_006713233 NM_001172566 NP_001166037 NM_001172567 NP_001166038 NM_001172568 NP_001166039 NM_001172569 NP_001166040 NM_002468 NP_002459
Function Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine. {ECO:0000269|PubMed:15361868, ECO:0000269|PubMed:18292575, ECO:0000269|PubMed:19506249, ECO:0000269|PubMed:9013863}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15361868, ECO:0000269|PubMed:15492225}.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:8957090}.
Top Pathways Herpes simplex infection, Legionellosis, Tuberculosis, Pertussis, Salmonella infection

Human-MYD88-cDNA-Clone - DC03657 from Abgent, a WuXi AppTec company

Prices $399.60
Sizes 10 µg
Species Human
Accession BC013589

MYD88 - MBS1277846 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC013589

Human MYD88 cDNA clone(NM_001172566.1) - CDFH012011 from Creative Biomart

Species Human
Accession NM_001172566.1

Human MYD88 cDNA clone(NM_001172567.1) - CDFH012012 from Creative Biomart

Species Human
Accession NM_001172567.1

Human MYD88 cDNA clone(NM_001172568.1) - CDFH012013 from Creative Biomart

Species Human
Accession NM_001172568.1

Human MYD88 cDNA clone(NM_001172569.1) - CDFH012014 from Creative Biomart

Species Human
Accession NM_001172569.1

Human MYD88 cDNA clone(NM_002468.4) - CDFH012015 from Creative Biomart

Species Human
Accession NM_002468.4

Human MYD88 ORF Clone(NM_002468.4) - CDCR283233 from Creative Biomart

Species Human
Accession NM_002468.4

Human MYD88 ORF Clone(NM_002468.4) - CDCR283236 from Creative Biomart

Species Human
Accession NM_002468.4

Human MYD88 ORF Clone(NM_001172566.1) - CDCR356555 from Creative Biomart

Species Human
Accession NM_001172566.1

Human MYD88 ORF Clone(NM_001172566.1) - CDCR356556 from Creative Biomart

Species Human
Accession NM_001172566.1

Human MYD88 ORF Clone(NM_001172567.1) - CDCR356557 from Creative Biomart

Species Human
Accession NM_001172567.1

Human MYD88 ORF Clone(NM_001172567.1) - CDCR356559 from Creative Biomart

Species Human
Accession NM_001172567.1

Human MYD88 ORF Clone(NM_001172568.1) - CDCR356560 from Creative Biomart

Species Human
Accession NM_001172568.1

Human MYD88 ORF Clone(NM_001172568.1) - CDCR356561 from Creative Biomart

Species Human
Accession NM_001172568.1

Human MYD88 ORF Clone(NM_001172569.1) - CDCR356562 from Creative Biomart

Species Human
Accession NM_001172569.1

Human MYD88 ORF Clone(NM_001172569.1) - CDCR356563 from Creative Biomart

Species Human
Accession NM_001172569.1

Mouse MYD88 ORF clone (NM_002468.4) - CDCL135701 from Creative biogene

Species Human

Mouse MYD88 ORF clone (NM_001172569.1) - CDCL135703 from Creative biogene

Species Human

Mouse MYD88 ORF clone (NM_001172567.1) - CDCL135705 from Creative biogene

Species Human

Mouse MYD88 ORF clone (NM_001172566.1) - CDCL135707 from Creative biogene

Species Human

Mouse MYD88 ORF clone (NM_001172568.1) - CDCL135709 from Creative biogene

Species Human

Human MYD88 ORF Clone (BC013589) - CDCS409007 from Creative biogene

Species Human
Accession Q99836

Human MYD88 cDNA Clone(NM_001172566.1) - CDFH012011 from Creative biogene

Species Human

Human MYD88 cDNA Clone(NM_001172567.1) - CDFH012012 from Creative biogene

Species Human
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