CDKN2B

Gene Symbol	CDKN2B
Entrez Gene	1030
Alt Symbol	CDK4I, INK4B, MTS2, P15, TP15, p15INK4b
Species	Human
Gene Type	protein-coding
Description	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
Other Description	CDK inhibitory protein|CDK4B inhibitor|MTS-2|cyclin-dependent kinase 4 inhibitor B|cyclin-dependent kinases 4 and 6 binding protein|multiple tumor suppressor 2|p14-INK4b|p14_CDK inhibitor|p14_INK4B|p15 CDK inhibitor|p15-INK4b|p15_INK4B
Swissprots	P42772 O15125 Q6FI09
Accessions	AAB32712 AAD14049 AAD14186 AAF28397 AAM44859 CAH59951 EAW58596 EAW58597 P42772 AF004819 AAB69989 AF488409 AF488410 AAO49471 AF488411 AF488731 AM392641 CAL37519 AM392962 CAL37840 AM393264 CAL38142 AM393391 CAL38269 BC014469 AAH14469 BC018984 BI560960 CR536529 CAG38766 JQ694046 AFN61601 JQ694047 AFN61602 JQ694048 AFN61603 JX391994 AGC10270 L36844 AAA50282 U17075 AAC50075 NM_004936 NP_004927 NM_078487 NP_511042
Function	Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:9230210}. Note=Also found in the nucleus.
Tissue Specificity	Isoform 2 is expressed in normal (keratinocytes, fibroblasts) and tumor cell lines. {ECO:0000269|PubMed:9230210}.
Top Pathways	Cell cycle, TGF-beta signaling pathway, Small cell lung cancer, HTLV-I infection, Viral carcinogenesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

p15 INK4b peptide - ab109892 from Abcam Category Peptide

CDKN2B / p15 INK4b Antibody Blocking Peptide - LS-E1819 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CDKN2B / p15 INK4b Antibody Blocking Peptide - LS-E1820 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CDKN2B / p15 INK4b Antibody Blocking Peptide - LS-E3007 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CDKN2B / p15 INK4b Antibody Blocking Peptide - LS-E3959 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CDKN2B / p15 INK4b Antibody Blocking Peptide - LS-E10519 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CDKN2B / p15 INK4b Antibody Blocking Peptide - LS-E27798 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human p15INK4b/CDKN2B Protein - H00001030-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CDKN2B-Antibody-C-term-Blocking-peptide - BP12630b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CDKN2B-Antibody-N-term-Blocking-peptide - BP12629a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CDKN2B-Antibody-C-term-Blocking-peptide - BP14138b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CDKN2B-Antibody-C-term-Blocking-Peptide - BP16165b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CDKN2B Blocking Peptide - 33R-7871 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

p15 Treponema pallidum (His tag) - 80-1369 from Fitzgerald Prices $195.00, $895.00 Sizes 100 µg, 1 mg Source E.coli

p15 INK4b Peptide - AC21-2859-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CDKN2B / p15INK4b - H00001030-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CDKN2B / p15INK4b - H00001030-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CDKN2B fusion protein - Ag3557 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

CDKN2B fusion protein - ag16059 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human CDKN2B, GST-tagged - CDKN2B-11063H from Creative Biomart Category Protein Source E.coli Species Human

p15 INK4b Blocking Peptide - CBP1212 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Monkey, Pig

p15 INK4b (G113) Peptide - BS1267P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Cyclin-dependent kinase 4 inhibitor B(CDKN2B) - CSB-YP005092HU CSB-EP005092HU CSB-BP005092HU CSB-MP005092HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CDKN2B Protein - abx164191 from Abbexa Category Protein Species Human, Mouse, Rat

CDKN2B / p15INK4b (transcript variant 2) - TP317024 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

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