Gene Symbol | Tfpi |
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Entrez Gene | 21788 |
Alt Symbol | A630013F22Rik, AW552122, EPI, LACI |
Species | Mouse |
Gene Type | protein-coding |
Description | tissue factor pathway inhibitor |
Other Description | extrinsic pathway inhibitor|lipoprotein-associated coagulation inhibitor |
Swissprots | Q9Z2U8 O54819 |
Accessions | EDL27281 EDL27282 EDL27283 EDL27284 O54819 AF004833 AAC40035 AF016313 AAD01586 AK028356 BAC25901 AK034752 BAC28821 AK041472 AK084706 AK164207 AK167522 BC036146 AAH36146 BY307762 XM_006499145 XP_006499208 XM_006499146 XP_006499209 XM_006499147 XP_006499210 XM_006499148 XP_006499211 XM_006499149 XP_006499212 XM_006499150 XP_006499213 NM_001177319 NP_001170790 NM_001177320 NP_001170791 NM_011576 NP_035706 |
Function | Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted. |
Tissue Specificity | Isoform alpha is expressed in heart and spleen; isoform beta in heart and lung. |
Top Pathways | Complement and coagulation cascades |
TFPI (I-20) - sc-18714 from Santa Cruz Biotechnology
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TFPI Antibody [Unconjugated] - AF2975 from Novus Biologicals
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TFPI Antibody (372311) - MAB2975 from Novus Biologicals
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TFPI Antibody - abx103327 from Abbexa
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Anti-Tissue Factor Pathway Inhibitor (TFPI) - 20-2637 from ARP American Research Products
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Anti-Tissue Factor Pathway Inhibitor (TFPI) - 20-2638 from ARP American Research Products
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TFPI / LACI / EPI Antibody, Rabbit PAb - 50131-RP01-100 from Sino Biological
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TFPI Antibody, Rabbit MAb - 50131-R120-50 from Sino Biological
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TFPI Antibody, Rabbit MAb - 50131-R107-50 from Sino Biological
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TFPI Antibody, Rabbit PAb, Antigen Affinity Purified - 50131-T16-100 from Sino Biological
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Rabbit Anti-Tfpi Polyclonal antibody - CPB-121RM from Creative Diagnostics
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Polyclonal Antibody to Tissue Factor Pathway Inhibitor (TFPI) - PAA394Mu01 from Cloud-clone
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Biotin-Linked Antibody to Tissue Factor Pathway Inhibitor (TFPI) - PAA394Mu71 from Cloud-clone
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FITC-Linked Antibody to Tissue Factor Pathway Inhibitor (TFPI) - PAA394Mu81 from Cloud-clone
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Tissue Factor Pathway Inhibitor Antibody - abx129517 from Abbexa
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Tissue Factor Pathway Inhibitor, Monoclonal Antibody - MBS2025820 from MyBioSource
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TFPI antibody - orb43157 from Biorbyt
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Tissue Factor Pathway Inhibitor, Monoclonal Antibody - MBS2032020 from MyBioSource
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Tissue Factor Pathway Inhibitor (TFPI) Polyclonal Antibody - CAU27987 from Biomatik
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