ALKBH2

Gene Symbol ALKBH2
Entrez Gene 121642
Alt Symbol ABH2
Species Human
Gene Type protein-coding
Description alkB, alkylation repair homolog 2 (E. coli)
Other Description 2OG-Fe(II) oxy DC1|DNA oxidative demethylase ALKBH2|alkylated DNA repair protein alkB homolog 2|alpha-ketoglutarate-dependent dioxygenase alkB homolog 2|oxy DC1
Swissprots Q6NS38 A4PET2 Q5XLE3
Accessions CAG17897 CCQ43124 EAW97845 Q6NS38 AB277859 BAF56576 AI278638 AK309062 AY754389 AAV28301 BC070489 AAH70489 BM785502 BM790974 BM820131 BU623121 CN421655 DA182735 HQ447536 ADQ32022 XM_005253835 XP_005253892 XM_005253836 XP_005253893 NM_001001655 NP_001001655 NM_001145374 NP_001138846 NM_001145375 NP_001138847 NM_001205179 NP_001192108 NM_001205180 NP_001192109
Function Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1- ethenoadenine (in vitro). Has strong preference for double- stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron. {ECO:0000269|PubMed:12486230, ECO:0000269|PubMed:12594517, ECO:0000269|PubMed:16174769, ECO:0000269|PubMed:18432238, ECO:0000269|PubMed:18519673}.
Subcellular Location Nucleus {ECO:0000269|PubMed:12486230, ECO:0000269|PubMed:12594517}. Note=Detected in replication foci during S-phase.
Tissue Specificity Detected in colon, small intestine, ovary, testis, prostate, skeletal muscle, heart, liver and urinary bladder. {ECO:0000269|PubMed:12486230, ECO:0000269|PubMed:16174769}.

ALKBH2 (H-134) - sc-367208 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

ALKBH2 (V-13) - sc-161335 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ALKBH2 (V-13): sc-161335. Western blot analysis of ALKBH2 expression in non-transfected: sc-117752 (A) and human ALKBH2 transfected: sc-111420 (B) 293T whole cell lysates.

Anti-ABH2 antibody - ab105340 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-ABH2 antibody (ab105340) at 1 µg/mlLane 2 : Anti-ABH2 antibody (ab105340) at 2 µg/mlLane 1 : Human kidney tissue lysateLane 2 : Human kidney tissue lysateLysates/proteins at 15 µg per lane.

Anti-ABH2 antibody - ab117464 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab117464, at 5µg/ml,staining ABH2 in formalin fixed, paraffin embedded Human small intestine tissue by Immunohistochemistry.

Anti-ABH2 antibody - ab197152 from Abcam

Prices $370.00
Sizes 250 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ABH2 antibody (ab197152) at 1/500 dilutionLane 1 : Human fetal spleen lysateLane 2 : Human fetal liver lysateLane 3 : Human fetal kidney lysate

Anti-ABH2 antibody [EPR6177(2)] - ab154859 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6177(2)
All lanes : Anti-ABH2 antibody [EPR6177(2)] (ab154859) at 1/1000 dilutionLane 1 : Human fetal brain tissue lysateLane 2 : Human testis tissue lysateLane 3 : Human fetal brain tissue lysateLane 4 : HeLa cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-ABH2 antibody [hABH2-7] - ab49740 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone hABH2-7

Anti-ABH2 / ALKBH2 Antibody (aa108-157) - LS-C102399 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ALKBH2 antibody LS-C102399 Western blot of Fetal Brain lysate.

Anti-ABH2 / ALKBH2 Antibody (C-Terminus) IHC-plus™ - LS-B5316 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ALKBH2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5316 concentration 5 ug/ml.

ABH2 Antibody - NBP1-56921 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ABH2 Antibody [NBP1-56921] - Human Brain lysate, concentration 0.2-1 ug/ml.

ABH2 Antibody - NBP1-76276 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: ABH2 Antibody [NBP1-76276] - Human kidney tissue lysate with ALKBH2 antibody at (A) 1 and (B) 2 ug/mL.

Anti-ALKBH2 antibody produced in rabbit - SAB2100107 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ALKBH2: <B>Cat. No.SAB2100107</B>: ALKBH2 in Fetal Brain tissue lysate with ALKBH2 antibody at 1.0 μg/mL.

Anti-ALKBH2 antibody produced in rabbit - SAB3500534 from Sigma-Aldrich

Prices $347.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ALKBH2: <B>Cat. No. SAB3500534</B>: ALKBH2 in human kidney tissue lysate with ALKBH2 antibody at (A) 1 and (B) 2 μg/mL.

Monoclonal Anti-hABH2 antibody produced in mouse - A8228 from Sigma-Aldrich

Prices $403.50
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone hABH2-7
<B>Immunoblotting</B><BR/>293T cell extract was separated on SDS-PAGE and probed with Monoclonal PA to HABH2 (MO) CL: HABH2-7 (<B>Cat. No. A8228</B>). The antibody was developed with Biotin APA M IgG (Fab+Fc) kit comp. (<B>Cat. No. B6398</B>), Alk Phos ExtrAvidim (<B>Cat. No. E2636</B>) and NBT/BCIP substrate. <BR/>Antibody dilution 2 μg/mL.

ALKBH2 antibody - middle region (ARP51778_P050) - ARP51778_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ALKBH2 Antibody - C-terminal region (ARP51779_P050) - ARP51779_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ALKBH2 antibody - GTX85166 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-ALKBH2 antibody used in Western blot. GTX85166

ALKBH2 antibody - 70R-4415 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

ALKBH2 antibody - orb75470 from Biorbyt

Prices $723.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of human kidney tissue lysate at (A) 1 and (B) 2 ug/mL using ALKBH2 antibody

ALKBH2 / ABH2 (C-term) antibody - AP26246PU-N from Acris Antibodies

Prices $340.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of ALKBH2 in human kidney tissue lysate with ALKBH2 antibody at (A) 1 and (B) 2 μg/ml.

ALKBH2 / ABH2 (C-term) antibody - AP31224PU-N from Acris Antibodies

Prices $430.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

ALKBH2 / ABH2 antibody - H00121642-B01P from Acris Antibodies

Prices $1,530.00
Sizes 500 µg
Host Mouse
Clonality Polyclonal
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