ALKBH2

Gene Symbol	ALKBH2
Entrez Gene	121642
Alt Symbol	ABH2
Species	Human
Gene Type	protein-coding
Description	alkB, alkylation repair homolog 2 (E. coli)
Other Description	2OG-Fe(II) oxy DC1|DNA oxidative demethylase ALKBH2|alkylated DNA repair protein alkB homolog 2|alpha-ketoglutarate-dependent dioxygenase alkB homolog 2|oxy DC1
Swissprots	Q6NS38 A4PET2 Q5XLE3
Accessions	CAG17897 CCQ43124 EAW97845 Q6NS38 AB277859 BAF56576 AI278638 AK309062 AY754389 AAV28301 BC070489 AAH70489 BM785502 BM790974 BM820131 BU623121 CN421655 DA182735 HQ447536 ADQ32022 XM_005253835 XP_005253892 XM_005253836 XP_005253893 NM_001001655 NP_001001655 NM_001145374 NP_001138846 NM_001145375 NP_001138847 NM_001205179 NP_001192108 NM_001205180 NP_001192109
Function	Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1- ethenoadenine (in vitro). Has strong preference for double- stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron. {ECO:0000269|PubMed:12486230, ECO:0000269|PubMed:12594517, ECO:0000269|PubMed:16174769, ECO:0000269|PubMed:18432238, ECO:0000269|PubMed:18519673}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:12486230, ECO:0000269|PubMed:12594517}. Note=Detected in replication foci during S-phase.
Tissue Specificity	Detected in colon, small intestine, ovary, testis, prostate, skeletal muscle, heart, liver and urinary bladder. {ECO:0000269|PubMed:12486230, ECO:0000269|PubMed:16174769}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ABH2 peptide - ab139425 from Abcam Category Peptide Prices $176.00 Sizes 50 µg

Human ABH2 full length protein - ab105622 from Abcam Category Protein Prices $297.00, $866.00 Sizes 100 µg, 500 µg Source E. coli Species Human

ABH2 / ALKBH2 Antibody Blocking Peptide - LS-E30975 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ABH2 / ALKBH2 Antibody Blocking Peptide - LS-E18566 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ABH2 Blocking Peptide - NBP1-76276PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Recombinant Human ABH2 Protein - NBP1-72287 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E.coli Species Human

ABH2 Recombinant Protein - P3431 from Novus Biologicals Category Protein Prices $549.00 Sizes 100 µg Species Human

ALKBH2 Peptide - GTX85166-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

Human ALKBH2 protein - orb167881 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

ALKBH2 Blocking Peptide - 33R-9735 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ALKBH2 protein (His tag) - 80R-1773 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

ALKBH2 / ABH2 (1-261, His-tag) - AR09956PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

ALKBH2 / ABH2 (1-261, His-tag) - AR09956PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

ALKBH2 / ABH2 - P3431 from Acris Antibodies Category Protein Prices $500.00 Sizes 100 µg Species Human

ALKBH2 / ABH2 control peptide - AP26246CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

ALKB Alkylation Repair Homolog 2, Human Recombinant - 228-12264-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

ALKBH2, 1-261aa, Human, His tag, E.coli - 01-2191-2 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

ALKBH2 Peptide - 5871P from ProSci Category Peptide Species Human

ALKBH2 fusion protein - ag12108 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ALKBH2 fusion protein - ag12081 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

ALKBH2 Human - ENPS-119 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human ALKB Alkylation Repair Homolog 2 Protein - BP002579-ENZ-112 from Syd Labs Category Protein Prices $160.00, $2,700.00 Sizes 20 µg, 1 mg Source E. coli-derived. Species Human

ALKBH2 Human Protein - GWB-BSP127 from Genway Biotech Category Protein Prices $75.00, $165.00, $3,230.00 Sizes 5 μg, 20 μg, 1000 μg Source Escherichia Coli. Species Human

ALKBH2, 1-261aa, Recombinant Protein - GWB-P1022H from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

Recombinant Human ALKBH2, His-tagged - ALKBH2-26040TH from Creative Biomart Category Protein Source E. coli

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