ALKBH2

Gene Symbol ALKBH2
Entrez Gene 121642
Alt Symbol ABH2
Species Human
Gene Type protein-coding
Description alkB, alkylation repair homolog 2 (E. coli)
Other Description 2OG-Fe(II) oxy DC1|DNA oxidative demethylase ALKBH2|alkylated DNA repair protein alkB homolog 2|alpha-ketoglutarate-dependent dioxygenase alkB homolog 2|oxy DC1
Swissprots Q6NS38 A4PET2 Q5XLE3
Accessions CAG17897 CCQ43124 EAW97845 Q6NS38 AB277859 BAF56576 AI278638 AK309062 AY754389 AAV28301 BC070489 AAH70489 BM785502 BM790974 BM820131 BU623121 CN421655 DA182735 HQ447536 ADQ32022 XM_005253835 XP_005253892 XM_005253836 XP_005253893 NM_001001655 NP_001001655 NM_001145374 NP_001138846 NM_001145375 NP_001138847 NM_001205179 NP_001192108 NM_001205180 NP_001192109
Function Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1- ethenoadenine (in vitro). Has strong preference for double- stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron. {ECO:0000269|PubMed:12486230, ECO:0000269|PubMed:12594517, ECO:0000269|PubMed:16174769, ECO:0000269|PubMed:18432238, ECO:0000269|PubMed:18519673}.
Subcellular Location Nucleus {ECO:0000269|PubMed:12486230, ECO:0000269|PubMed:12594517}. Note=Detected in replication foci during S-phase.
Tissue Specificity Detected in colon, small intestine, ovary, testis, prostate, skeletal muscle, heart, liver and urinary bladder. {ECO:0000269|PubMed:12486230, ECO:0000269|PubMed:16174769}.

ALKBH2-Over-expression-Lysate - LY15947a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag ALKBH2 (arrow) using his tag antibody. 293T cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ALKBH2 gene‘

ALKBH2 overexpression lysate - LY400362 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

ALKBH2 overexpression lysate - LY428853 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

ALKBH2 overexpression lysate - LY428854 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

ALKBH2 293 Cell Lysate - 400391 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg
Species Escherichia coli

ABH2 Overexpression Lysate (Native) - NBL1-07473 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: ABH2 Overexpression Lysate (Adult Normal) [NBL1-07473] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ABH2.

ALKBH2 (h): 293T Lysate - sc-111420 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

ALKBH2 Over-expression Lysate Product - GWB-A1D9FB from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

ABH2 Overexpression Lysate (Native) - NBP2-11351 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: ABH2 Overexpression Lysate (Adult Normal) [NBP2-11351] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ABH2.

ABH2 Overexpression Lysate (Native) - NBP2-11350 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: ABH2 Overexpression Lysate (Adult Normal) [NBP2-11350] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ABH2.

Panoply™ Human ALKBH2 Knockdown Stable Cell Line - CSC-DC000512 from Creative biogene

Category Cell Line
Species Human

Human ALKBH2 Knockout Cell Line-HEK293T - CSC-RT1422 from Creative biogene

Category Cell Line
Species Human

ALKBH2 KO Cell Lysate-HEK293T - CLKO-1272 from Creative biogene

Category Cell Lysate
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