Nfe2l2

Gene Symbol Nfe2l2
Entrez Gene 18024
Alt Symbol AI194320, Nrf2
Species Mouse
Gene Type protein-coding
Description nuclear factor, erythroid derived 2, like 2
Other Description NF-E2-related factor 2|NFE2-related factor 2|nuclear factor erythroid 2-related factor 2
Swissprots Q60795 Q3UQK0
Accessions AAC52983 EDL27192 EDL27193 EDL27194 Q60795 AK029360 AK142347 BAE25040 AK144247 BC003340 AAH03340 BC026943 AAH26943 BC057948 BY792550 U20532 AAA68291 NM_010902 NP_035032
Function Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region. {ECO:0000269|PubMed:9887101}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:9887101}. Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978, ECO:0000269|PubMed:9887101}. Note=Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents.
Tissue Specificity Widely expressed. Highest expression in liver, skeletal muscle, luminal cells of the stomach and intestine, lining of the bronchi and alveoli, and in renal tubules; followed by heart, spleen, testis and brain.
Top Pathways Protein processing in endoplasmic reticulum

Nrf2 CRISPR/Cas9 KO Plasmid (m) - sc-421869 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Nrf2 HDR Plasmid (m) - sc-421869-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Nrf2 Double Nickase Plasmid (m) - sc-421869-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Nrf2 Double Nickase Plasmid (m2) - sc-421869-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Nrf2 CRISPR Activation Plasmid (m) - sc-421869-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Nrf2 CRISPR Activation Plasmid (m2) - sc-421869-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Nrf2 Lentiviral Activation Particles (m) - sc-421869-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Nrf2 Lentiviral Activation Particles (m2) - sc-421869-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Nrf2 siRNA (m) - sc-37049 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Nrf2 shRNA Plasmid (m) - sc-37049-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

Nrf2 shRNA (m) Lentiviral Particles - sc-37049-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU082841 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® Long Non-Coding esiRNA - EMNC006861 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN36398 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND36398 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

NFE2L2 siRNA (Mouse) - CRM2749 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse NFE2L2 (NM_010902.3) - SHH351792 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Nfe2l2(NM_010902.3) - SHR006386 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse NFE2L2 siRNA - orb282225 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

NFE2L2 shRNA Plasmid (Mouse) - CHM2749 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

NFE2L2 miRNA 3'UTR clone - MiUTR1M-07625 from Creative biogene

Species Reactivities Mouse
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