KCNJ5

Gene Symbol KCNJ5
Entrez Gene 3762
Alt Symbol CIR, GIRK4, KATP1, KIR3.4, LQT13
Species Human
Gene Type protein-coding
Description potassium channel, inwardly rectifying subfamily J, member 5
Other Description G protein-activated inward rectifier potassium channel 4|IRK-4|cardiac ATP-sensitive potassium channel|heart KATP channel|inward rectifier K+ channel KIR3.4|potassium inwardly-rectifying channel, subfamily J, member 5
Swissprots Q6DK13 B2R744 Q6DK14 P48544 Q92807
Accessions EAW67726 EAW67727 P48544 AB690268 BAL72885 AK312837 BAG35691 BC069386 AAH69386 BC069482 AAH69482 BC069499 AAH69499 BC069571 AAH69571 BC074838 AAH74838 BC074839 AAH74839 BC096834 AAH96834 BX647543 D50134 BAA08814 HQ447428 ADQ31914 JN859132 AFB82769 JN859133 AFB82770 L47208 AAB07269 U39195 AAB53093 X83582 CAA58565 XM_011542809 XP_011541111 XM_011542810 XP_011541112 NM_000890 NP_000881
Function This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Islets, exocrine pancreas and heart. Expressed in the adrenal cortex, particularly the zona glomerulosa. {ECO:0000269|PubMed:21311022}.
Top Pathways Dopaminergic synapse, Morphine addiction, Retrograde endocannabinoid signaling, Circadian entrainment, Estrogen signaling pathway

KIR3.4 (A-14) - sc-23635 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

KIR3.4 (H-60) - sc-50411 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
KIR3.4 (H-60): sc-50411. Western blot analysis of KIR3.4 expression in HeLa (A) and Caki-1 (B) whole cell lysates.

Anti-KCNJ5 antibody - ab81114 from Abcam

Host Rabbit
Clonality Polyclonal
ab81114 staining KCNJ5 in mouse atria tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde, permeabilized with 0.5% Triton in PBS and blocked with 2% serum for 2 hours at 20°C; antigen retrieval was by heat mediation in a sodium citrate buffer. Samples were incubated with primary antibody (1/500 in 1% serum) for 16 hours at 4°C. An Alexa Fluor® 647-conjugated goat anti-rabbit IgG polyclonal (1/200) was used as the secondary antibody.See Abreview

Anti-KCNJ5 antibody - ab113699 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-KCNJ5 antibody (ab113699) at 1 µg/mlLane 1 : Testis (Human) Tissue Lysate - adult normal tissue (ab30257)Lane 2 : A498 (Human Kidney Carcinoma) Whole Cell LysateLane 3 : MCF7 (Human breast adenocarcinoma cell line) Whole Cell LysateLane 4 : A549 (Human lung adenocarcinoma epithelial cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-KCNJ5 antibody - ab75238 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-KCNJ5 antibody (ab75238) at 1/500 dilutionLane 1 : Extracts from HeLa cellsLane 2 : Extracts from HeLa cells with immunising peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-KCNJ5 antibody - ab66504 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNJ5 / Kir3.4 / GIRK4 Antibody (N-Terminus) - LS-C144784 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNJ5 / Kir3.4 / GIRK4 Antibody (aa374-419) - LS-C313807 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KCNJ5 / Kir3.4 / GIRK4 Antibody (N-Terminus) - LS-C109992 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
KCNJ5 / Kir3.4 antibody LS-C109992 Western blot of Fetal Liver lysate.

Anti-KCNJ5 / Kir3.4 / GIRK4 Antibody (clone 8D2) - LS-C197573 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 8D2
KCNJ5 monoclonal antibody (M01), clone 8D2. Western Blot analysis of KCNJ5 expression in K-562.

Anti-KCNJ5 / Kir3.4 / GIRK4 Antibody (aa370-419) - LS-C120664 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of A549 cells, using KCNJ5 Antibody. The picture on the right is treated with the synthesized peptide.

Kir3.4 Antibody - NBP1-88082 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Kir3.4 Antibody [NBP1-88082] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Negative control (vector only transfected HEK293T lysate)<br/>Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY424464)

Kir3.4 Antibody - NBP1-88081 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Kir3.4 Antibody [NBP1-88081] - Analysis in control (vector only transfected HEK293T lysate) and kCNJ5 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

Kir3.4 Antibody - NBP1-20157 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Kir3.4 Antibody (8D2) - H00003762-M01-100ug from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 8D2

KCNJ5 Polyclonal Antibody - bs-9931R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Monoclonal Anti-KCNJ5 antibody produced in mouse - SAB1412722 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 8D2
<B>Immunoblotting</B><BR/>Anti-KCNJ5:<B>Cat. No. SAB1412722</B>: Antibody concentration: 1–5 μg/mL. Immunofluorescence band of ~48 kDa using K-562 lysate.

Anti-KCNJ5 antibody produced in rabbit - HPA017353 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-KCNJ5: <B>Cat. No. HPA017353</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human pancreas shows strong cytoplasmic and membranous positivity in exocrine glandular cells.

Anti-KCNJ5 antibody produced in rabbit - HPA014722 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-KCNJ5: <B>Cat. No. HPA014722</B>: Immunohistochemical staining of human pancreas shows strong membranous and cytoplasmic positivity in exocrine glandular cells.

Anti-KCNJ5 antibody produced in rabbit - SAB2101219 from Sigma-Aldrich

Prices $347.50
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-KCNJ5: <B>Cat. No.SAB2101219</B>: KCNJ5 in Fetal Liver tissue lysate with KCNJ5 antibody at 1.0 μg/mL.

Anti-KCNJ5, C-Terminal antibody produced in rabbit - SAB4501633 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-KCNJ5, C-Terminal: <B>Cat. No. SAB4501633</B>: Immunofluorescence of A549 cells using Anti-KCNJ5, C-Terminal antibody. Cells on the left were treated with the Anti-KCNJ5, C-Terminal antibody. Cells on the right (negative control) were treated with both Anti-KCNJ5, C-Terminal antibody and the synthesized immunogen peptide.

KCNJ5 antibody - N-terminal region (ARP35020_P050) - ARP35020_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

KCNJ5 Antibody - C-terminal region (ARP74601_P050) - ARP74601_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

KIR3.4 antibody [N2C3] - GTX103081 from GeneTex

Host Rabbit
Clonality Polyclonal

KCNJ5 Antibody (OAAF04895) - OAAF04895 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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